1. [Acute polyradiculoneuropathy of Guillain-Barré. Critical review of potential etiopathogeneses].
- Author
-
Guadagnino M and Petitto F
- Subjects
- Acute Disease, Adolescent, Animals, Antibodies analysis, Antigen-Antibody Complex analysis, Autoimmune Diseases etiology, Campylobacter Infections complications, Child, Cytomegalovirus Infections complications, Female, Gastrointestinal Diseases complications, Herpesviridae Infections complications, Herpesvirus 4, Human, Humans, Immune Sera pharmacology, Immunity, Cellular, Influenza, Human complications, Nerve Fibers, Myelinated pathology, Polyradiculoneuropathy immunology, Polyradiculoneuropathy pathology, Pregnancy, Rats, Spinal Nerves immunology, Spinal Nerves pathology, T-Lymphocytes immunology, Virus Diseases complications, Polyradiculoneuropathy etiology
- Abstract
The authors go over the etiopathogenetic hypothesis suggested, in the last years, a propos of the Guillain-Barrè syndrome. They point out that about two/thirds of cases are preceded by infectious symptoms of the upper respiratory and alimentary tracts, with prevailing viral etiology. The nervous lesion, which characterize the histology of the illness, seems related to immunological change. In particular one must emphasize the possibility that the Guillain-Barrè syndrome is an autoimmune disorder of delayed hypersensivity, the laboratoristics model of which is constituted from experimental allergic neuritis.
- Published
- 1985