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2. I TUMORI INFANTILI E DEGLI ADOLESCENTI: TREND DI INCIDENZA E STUDIO DI EVENTUALI CLUSTER. CONFRONTO TRA LE PROVINCE DI PALERMO E DI CALTANISSETTA NEL PERIODO 2007-2012

Author

Marotta C, Mazzucco W, Rudisi G, Mazzola S, MARRELLA, Alessandro, Tumino R, Spata E, Cusimano R, Vitale F, and Marotta C, Mazzucco W, Rudisi G, Mazzola S, Marrella A, Tumino R, Spata E, Cusimano R, Vitale F

Subjects
Tumori infantili, Registro Tumori, Incidenza, Cluster, Settore MED/42 - Igiene Generale E Applicata
Abstract

INTRODUZIONE: Nonostante i progressi nelle strategie terapeutiche e il conseguente miglioramento della sopravvivenza, i tumori infantili rappresentano un importante problema di salute pubblica. È stato effettuato un confronto tra l’incidenza dei tumori infantili (0-14 anni) e degli adolescenti (15-19 anni) nelle province di Palermo e di Caltanissetta, nel periodo 2007-2012. MATERIALI E METODI: Sono stati analizzati 453 nuovi casi di tumore maligno e i non maligni del SNC in soggetti

Published
2017

3. SENTIERI-ReNaM: Valutazione globale del carico di mesotelioma

Author

Binazzi A, GdL SENTIERI-ReNaM., Bruno, C, Comba, PAOLO GIOVANNI, Conti, S, Corfiati, M, Fazzo, L, Manno, V, Marinaccio, A, Menegozzo, S, Minelli, Giuditta, Pasetto, R, Pirastu, R, Zona, A, Angelillo, I, Canessa, Pa, Cauzillo, G, Cavone, D, Chellini, E, Cocchioni, M, De Michieli, P, Forastiere, F, Davoli, M, Di Giammarco, A, Gennaro, V, Giaimo, M, Gioffrè, F, Mangone, L, Mazzoleni, G, Mensi, C, Merler, E, Merletti, F, Merseburger, A, Miligi, L, Mirabelli, D, Musti, M, Negro, C, Nicita, C, Pascucci, C, Riboldi, Lorenzo, Romanelli, A, Schallemberg, G, Stracci, F, Trafficante, Luigi Alberto, and Tumino, R.

Subjects
Mesothelioma, Male, Risk, Epidemiology, Incidence, Asbestos, Burden of illness, Italy, National Priority Contaminated Sites - NPCSs, Carcinogens, Environmental, Confidence Intervals, Female, Health Surveys, Humans, Industry, Occupational Exposure, Registries, Environmental Exposure, Environmental Pollution, Hazardous Waste Sites, Public Health, Environmental and Occupational Health, Environmental and Occupational Health, Environmental, Carcinogens, Public Health
Published
2017

4. In 2014 cancer registration covers more than half of the Italian population [Nel 2014 la registrazione dei tumori in Italia è estesa a oltre la metà del Paese]

Author

Crocetti, E, Madeddu, A, Mangone, L, AIRTUM Working Group: : Autelitano, M, Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Cusimano, R, Dei Tos, A, Falcini, F, Ferretti, S: Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Magoni, M, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G: Tisano, F, Traina, A, Tumino, R, Usala, M, VITALE, Francesco, Vitarelli, S, Zanetti, R., Crocetti, E, Madeddu, A, Mangone, L, AIRTUM Working Group: : Autelitano, M, Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Cusimano, R, Dei Tos, A, Falcini, F, Ferretti, S: Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Magoni, M, Marchesi, C:, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G: Tisano, F, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
cancer incidence, Italian population, cancer registration, Settore MED/42 - Igiene Generale E Applicata
Published
2014

5. After the increasing trend in the Nineties, in Italy incidence of tumours in children (0-14 years) is decreasing [Dopo l'aumento registrato negli anni Novanta, in Italia l'incidenza dei tumori infantili (0-14 anni) è in diminuzione]

Author

Buzzoni, C, Ferretti, S, Dal Maso, L, AIRTUM Working Group: Autelitano, M, Bizzoco, S, Vercelli, M, Borciani, E, Candela, G, Cocchioni, M, Cremone, L, Crocetti, E, Crosignani, P, Cusimano, R, Dei Tos, A, Falcini, F, Federico, M, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tisano, F, Traina, A, Tumino, R, Usala, M, VITALE, Francesco, Vitarelli, S, Zanetti, R., Buzzoni, C, Ferretti, S, Dal Maso, L, AIRTUM Working Group: Autelitano, M, Bizzoco, S, Vercelli, M, Borciani, E, Candela, G, Cocchioni, M, Cremone, L, Crocetti, E, Crosignani, P, Cusimano, R, Dei Tos, A, Falcini, F, Federico, M, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tisano, F, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R

Subjects
cancer incidence, Tumours in children, tumours in children in italy, Settore MED/42 - Igiene Generale E Applicata
Published
2014

6. [SENTIERI-ReNaM: Discussion and concluding remarks]

Author

Zona, Amerigo, Fazzo, Lucia, Binazzi, Alessandra, Bruno, Caterina, Corfiati, Marisa, Comba, Pietro, Conti, Susanna, Menegozzo, Simona, Nicita, Carmela, Pasetto, Roberto, Pirastu, Roberta, Marinaccio, Alessandro, Binazzi A, GdL SENTIERI-ReNaM., Bruno, C, Comba, P, Conti, S, Corfiati, M, Fazzo, L, Manno, V, Marinaccio, A, Menegozzo, S, Minelli, G, Pasetto, R, Pirastu, R, Zona, A, Angelillo, I, Canessa, Pa, Cauzillo, G, Cavone, D, Chellini, E, Cocchioni, M, De Michieli, P, Forastiere, F, Davoli, M, Di Giammarco, A, Gennaro, V, Giaimo, M, Gioffrè, F, Mangone, L, Mazzoleni, G, Mensi, C, Merler, E, Merletti, F, Merseburger, A, Miligi, L, Mirabelli, D, Musti, M, Negro, C, Nicita, C, Pascucci, C, Riboldi, L, Romanelli, A, Schallemberg, G, Stracci, F, Trafficante, L, and Tumino, R.

Subjects
Male, Mesothelioma, Risk, Incidence, Asbestos, Environmental Exposure, Health Surveys, Carcinogens, Environmental, Environmental, Italy, Occupational Exposure, Hazardous Waste Sites, Carcinogens, Confidence Intervals, Humans, Industry, Female, Registries, Environmental Pollution
Abstract

SENTIERI-ReNaM Project analysed the incidence of malignant mesothelioma (MM) for the period 2000-2011 in 39 National Priority Contaminated Sites (NPCSs), and assessed the overall impact of mesothelioma in different types of NPCSs. In the study period, 2,683 incident cases of malignant mesothelioma were recorded: 1,998 males (74.5%), 685 females (25.5%). Excluding cases with non attributable exposure and those non interviewed, exposure was identified in 1,926 cases (70% of all cases): 1,541 males (occupational exposure: 1,414; environmental exposure: 82), 385 females (occupational exposure: 103; environmental exposure: 141). Women experienced mainly environmental and domestic exposures to asbestos. Standard Incidence Ratio (SIR) excesses were observed in men in 27 out of 39 NPCSs and defects in the remaining 12; in women, 20 NPCSs showed SIR excesses, defects in 15; in 4 NPCSs no MM cases occurred among female population. The highest rates were found in NPCSs with asbestos-cement plants (Broni and Casale Monferrato), respectively, 98 per 100,000 per year and 68.6 in men, 72.1 and 45.8 in women. Excluding these two sites, the highest incidence rates were found in the group with harbours and shipyards, where the rates were, respectively, 13.2 among men and 2.5 among women. The results of this report will be communicated to national and local institutions, as well as to NPCSs resident populations.

Published
2016

7. [Hodgkin lymphoma in Italian children and adolescents]

Author

Dal Maso, Luigino, Terracini, Benedetto, Mosso, MARIA LUISA, Buzzoni, Carlotta, Autelitano M, AIRTUM Working Group., Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Crocetti, E, Dei Tos AP, Falcini, F, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
Aged, 80 and over, Adult, Male, Adolescent, Incidence, Infant, Newborn, Infant, Middle Aged, Newborn, Prognosis, Hodgkin Disease, Survival Rate, Age Distribution, Italy, Risk Factors, Child, Preschool, 80 and over, Humans, Female, Aged, Child, Retrospective Studies, Sex Distribution, Preschool
Published
2016

8. AIRTUM - Italia 2015: 3 milioni di italiani vivono dopo una diagnosi di tumore, ma incidenza e mortalità sono in calo

Author

Dal Maso, Luigino, Buzzoni, Carlotta, Guzzinati, Stefano, Crocetti, Emanuele, Autelitano M, AIRTUM Working Group., Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Crocetti, E, Dei Tos, A, Falcini, F, Ferretti, Silvia, Fusco, Marco, Gennaro, V, Giacomin, A, Gola, GIAN LUIGI, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, Alessandro, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Ricci, Paola, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
Adult, Male, Epidemiology, Incidence, Environmental and Occupational Health, Middle Aged, Aged, Disease-Free Survival, Female, Humans, Italy, Neoplasms, Registries, Risk Factors, Sex Distribution, Survival Rate, Public Health, Environmental and Occupational Health, Public Health
Published
2016

9. [SENTIERI-ReNaM: Results]

Author

Binazzi, Alessandra, Zona, Amerigo, Marinaccio, Alessandro, Bruno, Caterina, Corfiati, Marisa, Fazzo, Lucia, Menegozzo, Simona, Nicita, Carmela, Pasetto, Roberto, Pirastu, Roberta, De Santisi, Marco, Comba, Pietro, Binazzi A, GdL SENTIERI-ReNaM., Bruno, C, Comba, PAOLO GIOVANNI, Conti, S, Corfiati, M, Fazzo, L, Manno, V, Marinaccio, A, Menegozzo, S, Minelli, G, Pasetto, R, Pirastu, R, Zona, A, Angelillo, I, Canessa, Pa, Cauzillo, G, Cavone, D, Chellini, E, Cocchioni, M, De Michieli, P, Forastiere, F, Davoli, M, Di Giammarco, A, Gennaro, V, Giaimo, M, Gioffrè, F, Mangone, L, Mazzoleni, G, Mensi, C, Merler, E, Merletti, F, Merseburger, A, Miligi, L, Mirabelli, D, Musti, M16, 17 Negro, C, Nicita, C, Pascucci, C, Riboldi, L, Romanelli, A, Schallemberg, G, Stracci, F, Trafficante, L, and Tumino, R.

Subjects
Male, Mesothelioma, Risk, Incidence, Asbestos, Environmental Exposure, Health Surveys, Carcinogens, Environmental, Environmental, Italy, Occupational Exposure, Hazardous Waste Sites, Carcinogens, Confidence Intervals, Humans, Industry, Female, Registries, Environmental Pollution
Abstract

Mesothelioma incidence has been analyzed in National Priority Contaminated Sites (NPCSs) to estimate the health impact of asbestos exposure on resident people. The burden of professional and environmental exposures has been identified through data of the Regional Operational Centres (CORs), made available by the Italian National Mesothelioma Registry (ReNaM). An excess of mesothelioma incidence is confirmed in sites with a known past history of direct use of asbestos, such as Balangero, Casale Monferrato, Broni, Bari-Fibronit, and in coastal areas, where shipyards, harbours and other industries that involved a wide use of asbestos are represented (e.g., Trieste, La Spezia, Venice, and Leghorn). An excess of mesothelioma has been observed in settings where the asbestos is not mentioned as contaminant in the decree that included these sites among NPCSs, such as Cengio and Saliceto in Northern Italy; Falconara Marittima and the Bacino Idrografico Fiume Sacco in the Central Italy; the Litorale Domizio Flegreo and Agro Aversano, Milazzo, and Gela in the Southern Italy. Observed excess in the various NPCSs confirms the large-scale occurrence in contaminated Italian sites of a significant amount of total mesothelioma cases observed at national level. The analysis of occupational risk in epidemiological studies with an ecological design helps in defining the contribution of different factors to the overall risk.

Published
2016

10. About 1,400 new cancer diagnosis in Italian children (0-14 years) are attended every year (7,000 in 5 years) [Ogni anno sono previste circa 1.400 nuove diagnosi di tumori maligni nei bambini italiani di età 0-14 anni (7.000 nel quinquennio)]

Author

Crocetti, E, Rondelli, R, Dal Maso, L, AIRTUM Working G.r.o.u.p. Collaborators: Autelitano, M, Bizzoco, S, Vercelli, M, Borciani, E, Buzzoni, C, Candela, G, Cocchioni, M, Cremone, L, Crosignani, P, Cusimano, R, Dei Tos, A, Falcini, F, Federico, M, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tisano, Traina, A, Tumino, R, Usala, M, VITALE, Francesco, Vitarelli, S, Zanetti, R., Crocetti, E, Rondelli, R, Dal Maso, L, AIRTUM Working Group. Collaborators: Autelitano, M, Bizzoco, S, Vercelli, M, Borciani, E, Buzzoni, C, Candela, G, Cocchioni, M, Cremone, L, Crosignani, P, Cusimano, R, Dei Tos, A, Falcini, F, Federico, M, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tisano, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
cancer incidence, cancer in italian children, Settore MED/42 - Igiene Generale E Applicata, cancer in children
Published
2013

11. [Cancer survival in Italy in 2000-2007 is better than in Europe]

Author

Buzzoni, Carlotta, Crocetti, Emanuele, De Angelis, Roberta, Dal Maso, Luigino, Autelitano M, AIRTUM Working Group., Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Crocetti, E, Dei Tos, A, Falcini, F, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
Adult, Europe, Male, Survival Rate, Italy, Neoplasms, Female, Humans, Registries, Retrospective Studies
Published
2015

12. [AIRTUM and SIE for a shared definition of haemolymphopoietic cancers]

Author

Torrisi, Antonina, Castaing, Marine, Giacomin, Adriano, Luminari, Stefano, Mangone, Lucia, Autelitano, M, Bizzoco, S, Bonelli, L, Borciani, E, Buzzoni, C, Candela, G, Cavalieri D'Oro, L, Cocchioni, M, Coviello, V, Cremone, L, Crocetti, E, Dei Tos, A, Falcini, F, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, AIRTUM Working Group, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, and Zanetti, R.

Subjects
Societies, Scientific, Italy, Risk Factors, Humans, Population Surveillance, Public Health, Registries, Risk Assessment, Sicily, Hematologic Neoplasms, Scientific, Societies
Published
2015

14. Utilizzo di un questionario come strumento di confrontabilità tra un registro tumori di popolazione (RT) e il registro regionale specializzato dei Mesoteliomi (COR)

Author

Nicita, C., Chellini, E, Buzzoni, C, Caldarella, A, Giovannetti, L, Intrieri, T, Martini, A, Mensi, C., Tisano, F., Auteliano, M, Bisanti, L, Candela, G, Cappelletti, M, Cirilli, C, Contrino, Ml, F, Donato, Francesco, Falcini, F, Ferretti, S, Fusco, M, Giacomin, A, La Rosa, F, Limina, Rosa Maria, Madeddu, A, Mangone, L, Michiara, Am, Pannozzo, F, Piffer, S, Ricci, P, Serraino, D, Tessandori, R, Tumino, R, Vercelli, M, Vitarelli, S, Zambon, P, Zanetti, R, Cavone, D, Cocchioni, M, Consonni, D, De Zotti, R, Forastiere, F, Gennaro, V, Marinaccio, A, Menegozzo, M, Merletti, F, Mirabelli, D, Musti, M, Pascucci, C, Romanelli, A, Schallenberg, G, and Tumino, R.

Subjects
registro tumori di popolazione, Questionario, registro regionale specializzato dei Mesoteliomi
Published
2011

15. Confronto fra registri specializzati e registri tumori di popolazione: i risultati del progetto ReNaM-AIRTUM = A comparative analysis between regional mesothelioma registries and cancer registries: results of the ReNaM-AIRTUM project

Author

Nicita, C, Buzzoni, C, Chellini, E, Ferretti, S, Marinaccio, A, Mensi, C, AIRTUM Working Group, ReNaM Working Group, Progetto ReNaM AIRTUM Working Group, Autelitano, M, Bizzoco, S, Bonelli, L, Borciani, E, Candela, G, Cavalieri D’oro, L, Cocchioni, Mario, Coviello, V, Cremone, L, Crocetti, E, Cusimano, R, Dei Tos AP, Falcini, F, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Marchesi, C, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, Ponz de Leon, M, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tagliabue, G, Tisano, F, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, Susanna, Zanetti, R, and Progetto ReNaM AIRTUM Working

Published
2014

16. Lung cancer incidence in young women (20-49 years) reached incidence in young men

Author

Maso, Dal, Luigino, Autelitano, M, Bizzoco, S, Vercelli, M, Borciani, E, Buzzoni, C, Candela, G, Cocchioni, M, Cremone, L, Crocetti, E, Crosignani, P, Cusimano, R, Dei Tos, A, Falcini, F, Federico, Massimo, Ferretti, S, Fusco, M, Gennaro, V, Giacomin, A, Gola, G, La Rosa, F, Madeddu, A, Magoni, M, Mangone, L, Maspero, S, Mazzoleni, G, Melcarne, A, Merletti, F, Michiara, M, Minerba, S, Pannozzo, F, Piffer, S, PONZ DE LEON, Maurizio, Quarta, F, Ricci, P, Russo, A, Sampietro, G, Sciacca, S, Sechi, O, Serraino, D, Sutera Sardo, A, Tisano, F, Traina, A, Tumino, R, Usala, M, Vitale, F, Vitarelli, S, Zanetti, R., Dal Maso, L, and AIRTUM Working Group Collaborators, including Vitale, F.

Subjects
Male, Lung Neoplasms, cancro nelle giovani donne, young, Incidence, Adenocarcinoma, Lung cancer, incidence, young, cancro nei giovani uomini, Settore MED/42 - Igiene Generale E Applicata, incidenza del ca polmonare, Italy, incidence, Humans, Female, Lung cancer
Abstract

Il grafico, basato sui dati AIRTUM 1992- 2007,mostra l’andamento dell’incidenza di tumore del polmone nei giovani adulti di età 20-49 anni in entrambi i sessi. I

Published
2013

17. Italian cancer figures, report 2011: Survival of cancer patients in Italy

Author

Fusco, M, Buzzoni, C, Coviello, E, Rashid, I, Bianconi, F, Cuccaro, F, Castaing, M, De Angelis, R, Giacomin, A, Guzzinati, S, Mosso, Ml, Pisani, P, Quaglia, A, Randi, G, Ramazzotti, V, Russo, A, Senatore, G, Stracci, F, Traina, A, Vercelli, M, Zarcone, M, Ferretti, S, Mazzoleni, G, Bellú, F, Tschugguel, B, De Valiere, E, Facchinelli, G, Falk, M, Dal Cappello, T, Vercellino, Pc, Andreone, S, Busato, A, Marzola, L, Migliari, E, Carletti, N, Nenci, I, Crocetti, E, Caldarella, A, Corbinelli, A, Giusti, F, Intrieri, T, Manneschi, G, Nemcova, L, Romeo, G, Sacchettini, C, Zappa, M, Paci, E, Serraino, D, Angelin, T, Bidoli, E, Dal Maso, L, de Dottori, M, De Paoli, A, De Santis, E, Forgiarini, O, Lise, M, Zucchetto, A, Zanier, L, Orengo, Ma, Casella, C, Marani, E, Puppo, A, Celesia, Mv, Cogno, R, Manenti, S, Garrone, E, Pannozzo, F, Busco, S, Cercato, Mc, Battisti, W, Sperduti, I, Macci, L, Bugliarello, E, Bernazza, E, Tamburo, L, Rossi, M, Curatella, S, De Francesco, C, Tamburrino, S, Bisanti, L, Autelitano, M, Ghilardi, S, Leone, R, Filipazzi, L, Bonini, A, Giubelli, C, Federico, M, Artioli, Me, Valla, K, Braghiroli, B, Cirilli, C, Luminari, S, Pirani, M, Ferrari, L, Bellatalla, C, Panico, M, Perrotta, C, Vassante, B, Vitale, Mf, Michiara, M, Bozzani, F, Sgargi, P, Tumino, R, La Rosa MG, Cascone, G, Frasca, G, Giurdanella, Mc, Martorana, C, Morana, G, Nicita, C, Rollo, Pc, Ruggeri, Mg, Sigona, A, Spata, E, Vacirca, S, Mangone, L, Di Felice, E, Pezzarossi, A, Caroli, S, Pellegri, C, Vicentini, M, Storchi, C, Cavuto, S, Costa, J, Falcini, F, Colamartini, A, Bucchi, L, Balducci, C, Ravegnani, M, Vitali, B, Cordaro, C, Caprara, L, Giuliani, O, Giorgetti, S, Salvatore, S, Palumbo, M, Vattiato, R, Ravaioli, A, Foca, F, Rinaldi, E, Mancini, S, Tonelli, C, Amadori, M, Cremone, L, Iannelli, A, Zevola, A, Budroni, M, Cesaraccio, R, Pirino, D, Carboni, D, Fiori, G, Soddu, M, Mameli, G, Mura, F, Contrino, Ml, Madeddu, A, Tisano, F, Sciacca, S, Muni, A, Mizzi, M, Russo, M, Sacco, G, Aletta, P, Colanino Ziino, A, Tessandori, R, Fanetti, Ac, Maspero, S, Annulli, Ml, Moroni, E, Sanoja Gonzalez ME, Zanetti, R, Rosso, S, Patriarca, S, Prandi, R, Sobrato, I, Gilardi, F, Busso, P, Piffer, S, Gentilini, Ma, Battisti, L, Rizzello, R, Cappelletti, M, Moser, M, La Rosa, F, D'Alò, D, Scheibel, M, Costarelli, D, Spano, F, Rossini, S, Santucci, C, Petrinelli, Am, Solimene, C, Brunori, V, Crosignani, P, Tagliabue, G, Contiero, P, Preto, L, Tittarelli, A, Maghini, A, Codazzi, T, Frassoldi, E, Gada, D, Costa, E, di Grazia, L, Zambon, P, Baracco, M, Bovo, E, Dal Cin, A, Fiore, Ar, Greco, A, Monetti, D, Rosano, A, Stocco, C, Tognazzo, S, Donato, Francesco, Limina, Rosa Maria, Adorni, A, Andreis, P, Zani, G, Piovani, F, Salvi, O, Puleio, M, Vitarelli, S, Antonini, S, Candela, G, Pappalardo, G, Scuderi, T, Lottero, B, Ribaudo, M, Ricci, P, Guarda, L, Gatti, L, Bozzeda, A, Dall'Acqua, M, Pironi, V, Sutera Sardo, A, Mazzei, A, Sirianni, N, Lavecchia, Am, Mancuso, P, Usala, M, Pala, F, Sini, Gm, Pintori, N, Canu, L, Demurtas, G, Doa, N, Ponz de Leon, M, Domati, F, Rossi, G, Goldoni, Ca, Rossi, F, De Gaetani, C, Benatti, P, Roncucci, L, Di Gregorio, C, Pedroni, M, Pezzi, A, Maffei, S, Mariani, F, Borsi, E, Carruba, G, Cusimano, R, Amodio, R, Dolcemascolo, C, Staiti, R, Pastore, G, Magnani, C, Terracini, B, Cena, T, Alessi, D, Baussano, I, Merletti, F, Maule, M, Macerata, V, Cocchioni, M, Pascucci, C, Gennaro, V, Lazzarotto, A, Benfatto, L, Mazzucco, G, and Montanaro, F.

Subjects
Survival, Italy, cancer patients
Published
2011

23. Incidenza dei tumori ematologici nelle aree italiane

Author

Allemani, C., Minicozzi, P., DE ANGELIS, R., Tereanu, C., Berrino, F., Bellù, F., Cesaraccio, R., DE LISI, V., Donato, A., Falcini, F., Ferretti, S., Fiore, A. R., Fusco, M., Giacomin, A., Luminari, S., Mangone, L., Paci, E., Piffer, S., Scheibel, M., Serraino, D., Tumino, R., Vercelli, Marina, and Sant, R. ZANETTI E. M.

Published
2009

24. CAREMORE (Joint Community and Cancer Registry Model On Rehabilitation)

Author

DI SALVO, F., Baili, P., Ciampichini, R., Mangone, L., Vicentini, M., Tumino, R., Cilia, S., Vercelli, Marina, Orengo, M. A., Budroni, M., Contiero, P., Tagliabue, G., Aurora, F., DE LORENZO, F., Fattore, G., Fait, A., Compagni, A., Bufalino, R., Gatta, G., Sant, M., Saltarelli, S., and Micheli, A.

Subjects
cancer rehabilitation
Published
2009

29. I tumori negli anziani

Author

Vercelli, Marina, Zambon, P, Tumino, R, Tanda, F, Tittarelli, A, Federico, M, and Gruppo, Airt

Subjects
elderly patients cancers
Published
2002

30. [Dietary habits and cancer: the experience of EPIC-Italy].

Author

Sieri S, Agnoli C, Pala V, Mattiello A, Panico S, Masala G, Assedi M, Tumino R, Frasca G, Sacerdote C, Vineis P, and Krogh V

Subjects
Adult, Anthropometry methods, Breast Neoplasms epidemiology, Colorectal Neoplasms epidemiology, Diet Surveys, Diet, Mediterranean statistics & numerical data, European Union statistics & numerical data, Female, Follow-Up Studies, Humans, Incidence, Italy epidemiology, Male, Middle Aged, Neoplasms etiology, Neoplasms mortality, Prevalence, Prospective Studies, Registries statistics & numerical data, Risk Assessment, Risk Factors, Feeding Behavior, Neoplasms epidemiology, Societies, Medical
Abstract

Objectives: to investigate hypothesised relationships between diet and cancer by assessing diet as a whole, in the Italian cohort EPIC., Design: multicentric prospective study., Setting and Participants: 47,749 volunteers were recruited between 1993 and 1998 in the centres of Varese and Turin (Northern Italy), Florence (Central Italy), Naples and Ragusa (Southern Italy). Information on diet and lifestyle were collected through validated questionnaires. Anthropometric measurements were taken and biological samples collected using standardised protocols., Main Outcome Measures: follow-up was carried out by accessing regional cancer and mortality registries, hospital discharge records, and by telephone inquiries (only for Naples). After a median follow-up of 11 years, 879 incident cases of breast cancer, 421 cases of colorectal cancer, and 152 deaths were identified. Multivariate Cox regression models were used to estimate risks in relation to dietary characteristics., Results: the "Olive oil & Salad" dietary pattern, characterised by high consumption of raw vegetables and olive oil, was associated with a lower risk of overall mortality in the elderly. Adherence to a Mediterranean diet rich in vegetables and fruit was associated with reduced risk of colon cancer. Consumption of high-glycemic carbohydrates was associated with higher incidence of breast cancer and colorectal cancer. Reduced risk of colon cancer was also found in regular consumers of yoghurt., Conclusions: the accuracy and comprehensiveness of EPIC-Italy data made it possible to investigate both individual dietary components and dietary habits as a whole, to thereby provide Italians with dietary and lifestyle advice that will help them to remain healthy.

Published
2015

31. [Alcohol consumption and epithelial cancer risk in the EPIC-Italy cohort].

Author

Saieva C, Caini S, Ceroti M, Fasanelli F, Ricceri F, Agnoli C, Grioni S, Mattiello A, Santucci de Magistris M, Tumino R, Martorana C, and Masala G

Subjects
Adult, Breast Neoplasms epidemiology, Cohort Studies, Colorectal Neoplasms epidemiology, European Union, Female, Follow-Up Studies, Humans, Incidence, Incidental Findings, Italy epidemiology, Male, Middle Aged, Neoplasms diagnosis, Neoplasms etiology, Neoplasms, Glandular and Epithelial epidemiology, Prevalence, Prospective Studies, Prostatic Neoplasms epidemiology, Risk Assessment, Risk Factors, Sex Distribution, Smoking adverse effects, Surveys and Questionnaires, Time Factors, Alcohol Drinking adverse effects, Alcohol Drinking epidemiology, Neoplasms epidemiology
Abstract

Objectives: to evaluate the association between baseline and lifetime alcohol consumption and the risk of epithelial cancer (all types) in the Italian cohort of the European Prospective Investigation into Cancer and nutrition (EPIC) study., Design: prospective study carried out in a large Italian population., Setting and Participants: detailed information on the consumption of alcoholic beverages at baseline and over lifetime collected at enrolment into the EPIC study (1993-1998) by standardised questionnaires for 44,477 healthy adults., Main Outcomes Measures: 2,640 incident epithelial cancers identified during a mean follow-up of 11.4 years. Multivariate Cox proportional hazard models adjusted for several potential confounders were used to calculate hazard ratios (HR) and corresponding 95% confidence intervals (CI)., Results: lifetime alcohol consumption (p for trend =0.005) was associated with epithelial cancer risk in the whole cohort. This effect was more evident in women (p =0.049) and in current smokers (p =0.012). Alcohol consumption at baseline was associated with the epithelial cancer risk in women (p for trend =0.01) and current smokers (p for trend =0.02). A significant interaction between alcohol consumption and smoke duration (p =0.015 for baseline; p =0.006 for lifetime) was identified., Conclusions: in this large Italian population, alcohol consumption, particularly lifetime, is a significant risk factor for the development of epithelial cancers. This effect appears to be modulated by smoking habits.

Published
2015

32. [Epidemiologic surveillance of mesothelioma for the prevention of asbestos exposure also in non-traditional settings].

Author

Binazzi A, Scarselli A, Corfiati M, Di Marzio D, Branchi C, Verardo M, Mirabelli D, Gennaro V, Mensi C, Schallenberg G, Merler E, De Zotti R, Romanelli A, Chellini E, Pascucci C, D'Alò D, Forastiere F, Trafficante L, Menegozzo S, Musti M, Cauzillo G, Leotta A, Tumino R, Melis M, and Marinaccio A

Subjects
Epidemiological Monitoring, Female, Humans, Italy epidemiology, Lung Neoplasms etiology, Lung Neoplasms prevention & control, Male, Mesothelioma etiology, Mesothelioma prevention & control, Mesothelioma, Malignant, Middle Aged, Occupational Diseases etiology, Occupational Diseases prevention & control, Occupational Exposure adverse effects, Pleural Neoplasms etiology, Pleural Neoplasms prevention & control, Population Surveillance, Registries, Asbestos poisoning, Lung Neoplasms epidemiology, Mesothelioma epidemiology, Occupational Diseases epidemiology, Pleural Neoplasms epidemiology
Abstract

Objective: To show how malignant mesothelioma (MM) surveillance not only identifies settings of exposure representing past industrial history, but it may also detect conditions of current exposure relevant for the prevention, if the wide spectrum of asbestos uses is considered., Design: Active search of MM cases and exposure assessment at individual level through a questionnaire; identification of exposure circumstances relevant for prevention., Setting and Participants: Italy, all the Regions where a Regional Operating Centre (COR) is established to identify all MM cases diagnosed in the population and analyze their occupational, residential, household and environmental histories. Period of diagnosis: 1993-2008., Main Outcome Measures: Descriptive analysis of MM cases and of asbestos exposures., Results: ReNaM includes 15,845 cases of MM diagnosed between 1993 and 2008.The male/female ratio is 2.5. Mean age at diagnosis is 69 years. Pleural MMs represent 93% of all cases. Exposures have been investigated in 12,065 cases (76%). The median latency time is 46 years. In addition to clusters of MM cases in activities well known to entail asbestos use, different current exposure circumstances requiring intervention have been evidenced., Conclusions: On the basis of this experience, epidemiological surveillance of all occupational cancers should be implemented to foster synergies with the compensation system and the Local Health Authorities' occupational safety and health services, as required by the Italian Legislative Decree N. 81/2008.

Published
2013

34. [Considerations on the need for cooperation between Italian Association of Cancer Registries (AIRTUM) and the Italian National Mesothelioma Registry (RENAM)].

Author

Chellini E, Nicita C, and Tumino R

Subjects
Cooperative Behavior, Data Collection, Guidelines as Topic, Humans, Incidence, Italy epidemiology, Pilot Projects, Reproducibility of Results, Sicily epidemiology, Societies, Scientific organization & administration, Mesothelioma epidemiology, Neoplasms epidemiology, Pleural Neoplasms epidemiology, Registries
Abstract

Unlabelled: A pilot study comparing mesothelioma registries and population-based cancer registries of two Italian regions, Sicilia and Toscana, shows a good agreement on total number of registered incident cases. However, and in spite of the use of the same clinical sources of data, discrepancies were detected because of different criteria applied in collecting and classifying the relevant information on diagnoses. The development of common guidelines on the definition of mesothelioma case is a challenge for the Italian National Mesothelioma Registry (RENAM) and for the Italian Association of Cancer Registries (AIRTUM). The calendar period covered by the study was 1998- 2005 for Sicily and 1988-2005 for Tuscan., Keywords: cancer registries, mesothelioma, guidelines.

Published
2011

35. [Mortality from asbestos-related causes and incidence of pleural mesothelioma among former asbestos cement workers in San Filippo del Mela (Sicily)].

Author

Fazzo L, Nicita C, Cernigliaro A, Zona A, Bruno C, Fiumanò G, Villari C, Puglisi G, Marinaccio A, Comba P, and Tumino R

Subjects
Asbestos analysis, Asbestosis etiology, Asbestosis mortality, Female, Humans, Incidence, Lung Neoplasms epidemiology, Lung Neoplasms etiology, Lung Neoplasms mortality, Male, Mesothelioma etiology, Mesothelioma mortality, Occupational Exposure analysis, Pleural Neoplasms etiology, Pleural Neoplasms mortality, Sicily epidemiology, Asbestos adverse effects, Asbestosis epidemiology, Mesothelioma epidemiology, Occupational Exposure adverse effects, Pleural Neoplasms epidemiology
Abstract

Objectives: The present paper estimates the burden of asbestos-related disease among asbestos-cement production workers of the Sacelit plant that operated in San Filippo del Mela (Province of Messina) from 1958 through 1993., Setting and Participants: The cohort was enumerated by the local committee of formerly exposed workers, with whom a collaboration was set up. The cohort includes 198 subjects with complete individual anagraphic information, out of 231 previous workers identified by the committee. A record-linkage with the Sicilian centre of the National mesothelioma registry enabled estimation of mesothelioma incidence for the years 1998-2008. Standardised proportionate mortality (SPMR) for asbestos-related causes was computed for the years 1986-2009. Sicilian Region constituted the reference population. The rationale for using SPMR rather than standardized mortality ratio (SMR) was a consequence for the lack of company files from which to obtain dates of start and termination of employment, and thus to compute person-years of observation, following the guidelines of the international scientific literature., Results: Standardised incidence ratio (SIR) for mesothelioma in the overall cohort was 251 (4 observed, 0.02 expected). Proportionate mortality analysis among male subjects showed significant increases for pneumoconiosis (SPMR 80.1, 5 observed), lung cancer (SPMR 2.81, 10 observed) and pleural neoplasms (SPMR 19.4, 2 observed)., Conclusions: Notwithstanding limitations in cohort reconstruction, for which the proportion of eligible subjects was 87.5% of those detected by the local committee, and the lack of information on duration of employment, it was possible to estimate a significant increase of the incidence of pleural mesothelioma with respect to Sicilian population. Also mortality from asbestos-related causes was in excess with respect to the regional reference population.

Published
2010

36. [Epidemiological surveillance of malignant mesothelioma cases in Italy: incidence and asbestos exposure figures by the Italian mesothelioma registry (ReNaM)].

Author

Marinaccio A, Binazzi A, Cauzillo G, Chellini E, De Zotti R, Gennaro V, Menegozzo M, Mensi C, Merler E, Mirabelli D, Musti M, Pannelli F, Romanelli A, Scarselli A, Tosi S, Tumino R, and Nesti M

Subjects
Aged, Female, Humans, Incidence, Italy epidemiology, Male, Middle Aged, Population Surveillance, Registries, Asbestos adverse effects, Mesothelioma epidemiology, Mesothelioma etiology, Occupational Diseases epidemiology, Occupational Diseases etiology, Occupational Exposure adverse effects, Pleural Neoplasms epidemiology, Pleural Neoplasms etiology
Abstract

The Study describes the epidemiological surveillance of mesothelioma cases carried out by the Italian mesothelioma register (ReNaM). A Regional Operating Centre (COR) is present in nearly all Italian regions (17 out of 20) and it collects malignant mesothelioma cases and investigate the modalities of asbestos exposure by using a structured questionnaire. The register produces malignant mesothelioma incidence measures and analyses of the modalities of the asbestos exposure. The standardized incidence rate of malignant mesothelioma in 2001 was 2.98 (in 100,000 inhabitants) among men and 0.98 among women; a professional (certain, probable, possible) exposure has been detected in 67.4% of defined cases. In addition to the conventional sectors (shipbuilding, railways repair and demolition, asbestos-cement production), also textile, building, transport, chemical and glass industries, petroleum and sugar refineries, electricity production and distribution plants are getting involved. Despite the absence of some regions completing the national coverage and the non homogeneity in collecting and coding data, the epidemiological surveillance of malignant mesothelioma carried out by ReNaM is an important tool for the scientific knowledge and the prevention of asbestos-related diseases.

Published
2007

37. Quality and completeness indices.

Author

Tumino R and Ferretti S

Subjects
Aged, Aged, 80 and over, Death Certificates, Female, Humans, Incidence, Italy epidemiology, Male, Neoplasms, Unknown Primary epidemiology, Organ Specificity, Registries statistics & numerical data, Research Design, Survival Analysis, Neoplasms epidemiology, Quality Indicators, Health Care, Registries standards
Abstract

In the present study, time trends of the main quality indices in the pool of the Italian Network of Cancer Registries (pool AIRT) are presented for the period 1986-1997. The percentage of cases with morphological verification increased from 75% to 83% among males and from 77% to 85% among females. Cases known only from death certificates (DCO) decreased over time in both sexes; in recent years they were about 3% of the whole case-series. Mortality incidence ratio decreased over time, from 66% to 54% among males and from 55% to 48% among females. Also cases with unknown primary site showed a decreasing time tendency. Such quality indices are also presented for specific cancer sites and for elderly subjects (75+ years). The overall trends of quality indices showed an improvement in both the activity of Cancer Registries and of the Health System.

Published
2004

38. Cancer trends in Italy: figures from the cancer registries (1986-1997).

Author

Crocetti E, Capocaccia R, Casella C, Ferretti S, Guzzinati S, Rosso S, Sacchettini C, Spitale A, Stracci F, and Tumino R

Subjects
Adolescent, Adult, Age Distribution, Aged, Female, Humans, Incidence, Italy epidemiology, Male, Middle Aged, Sex Distribution, Neoplasms epidemiology, Registries statistics & numerical data
Abstract

The Italian Network of Cancer Registries analyzed incidence and mortality cancer trends during the period 1986-1997 Overall, 525,645 incident cancers and 269,902 cancer deaths (in subjects 15 years and older) were included. Age-adjusted rates, joinpoints (points in time where trend significantly changes from linearity) and estimated annual percent changes in rates (EAPC) were computed. Overall cancer incidence was significantly increasing in both sexes and cancer mortality was significantly decreasing (since 1991 among males). Incidence and mortality trends are summarised for single cancer sites. Crude rates are also showed to evaluate the effect of population ageing in terms of diagnostic and therapeutic burden for the National Health System.

Published
2004

39. Head and neck cancers: oral cavity, pharynx, and larynx.

Author

Tumino R and Vicario G

Subjects
Databases, Factual, Female, Humans, Incidence, Italy epidemiology, Laryngeal Neoplasms epidemiology, Male, Mouth Neoplasms epidemiology, Pharyngeal Neoplasms epidemiology, Registries statistics & numerical data, Retrospective Studies, Head and Neck Neoplasms epidemiology
Abstract

The present paper on head and neck cancers analyses oral cavity pharynx and larynx cancers in the database of the Italian Network of Cancer Registries (pool AIRT) during the period 1986-1997. The analysis of 7,234 oral cavity incident cases shows diverging trends between sexes; in fact, rates decrease significantly among males and increase among females. Oral cavity cancer mortality rates (3,032 deaths) significantly decrease in the period 1986-1997 in both sexes. As regards to pharynx (3,728 incident cases and 2,517 deaths), decreasing trends have been observed for both incidence and mortality, statistically significant only among males. Larynx cancers (9,842 incident cases and 3,946 deaths) showed a significant decreasing trend for both incidence and mortality, among males; trends are stable among females. In the present report we refer to head and neck cancers as those arising in the anatomical sites coded in ICDO-2 with C00-C14 (cancer of the lip, oral cavity and pharynx) and C32 (larynx). Such a grouping is justified, at least for epithelial histological types, as these cancers share a common series of risk factors: EBV, HPIV, smoke, alcohol, diet and professional exposures.

Published
2004

40. Building a database for survival analysis.

Author

Guzzinati S, Vitarelli S, Ramazzotti V, and Tumino R

Subjects
Adult, Child, Female, Humans, Italy epidemiology, Male, Registries, Databases, Factual, Neoplasms mortality, Survival Analysis
Abstract

The AIRT built a national data base for survival data, collecting follow up information regarding incident cases from 14 cancer registries and 2 childhood cancer registries operating in Italy. In this study, 210,661 cases incident during the period 1990-1994, followed up until 1999, were analysed. The Veneto Cancer Registry did the data quality checks, the conversion in SAS format and developed a SAS procedure to perform the survival analysis. The procedure allows to select the cancer registry, the period and the cancer site to analyse, running the Hakulinens' software for relative survival analysis and exporting the results in Excel sheet to produce a standard layout.

Published
2001

41. [Ultraviolet radiation and skin tumors].

Author

Zanetti R and Tumino R

Subjects
Animals, Carcinoma, Basal Cell prevention & control, Carcinoma, Squamous Cell prevention & control, Case-Control Studies, Dose-Response Relationship, Radiation, Humans, Melanoma prevention & control, Neoplasms, Radiation-Induced prevention & control, Occupational Diseases prevention & control, Risk Factors, Skin Neoplasms prevention & control, Time Factors, Carcinoma, Basal Cell etiology, Carcinoma, Squamous Cell etiology, Melanoma etiology, Neoplasms, Radiation-Induced etiology, Occupational Diseases etiology, Occupational Exposure, Skin Neoplasms etiology, Ultraviolet Rays adverse effects
Abstract

In the evaluation expressed by the IARC Monographs, solar radiation is recognised to be carcinogenic to man. The principal risk factors for skin cancers are personal characteristics such as fair complexion or tendency to burn. After controlling for these factors, an association remains with exposure to solar radiation, with different patterns for various types of skin cancer. For cutaneous malignant melanoma (CMM) the evidence is based on the results of two dozen case-control studies which showed a significant positive association for intermittent exposure (overall OR: 1.7), a reduced risk for heavy occupational exposure (OR: 0.8) and an increased risk with sunburns (OR: 1.9). For basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) the evidence is based on experimental results in animals, on descriptive studies (mainly body location and geographical distribution) and on a few case-control studies. The risk pattern of BCC is similar to that for CMM, with increased risk for intermediate levels of cumulative exposure and a protection associated with higher levels. Contrary wise, low and intermediate cumulative doses have no effect on the risk of SCC, which increases exponentially with very high doses like those corresponding to a lifelong outdoor occupational exposure.

Published
1998

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