1. [A thioridazine-dihydroergotoxine combination in the treatment of senile pruritus].
- Author
-
Polenghi M, Colombo MD, Barcella ML, and Perego M
- Subjects
- Administration, Oral, Animals, Anxiety, Cats, Depression, Dihydroergotoxine administration & dosage, Drug Combinations, Drug Evaluation, Humans, Male, Middle Aged, Pruritus psychology, Skin Temperature drug effects, Thioridazine administration & dosage, Dihydroergotoxine therapeutic use, Pruritus drug therapy, Thioridazine therapeutic use
- Abstract
Senile itching, a peculiar clinical situation consisting of a cutaneous senile involution associated with a relevant neurogenic component, still keeps being a difficult therapeutic problem. For the purpose, a clinical trial, carried out with a combination of thioridazine and dihydroergotoxine on 19 patients carriers of the affection, could show a relevant decrease in all parameters assessed, ie itching, muscle tension and skin temperature measured by biofeedback. The combination also showed a good tolerance.
- Published
- 1989