1. 糖尿病ラットにおけるバナデートの腎への効果
- Subjects
albumin excretion rate ,streptozotocin diabetes ,IgG 排泄率 ,バナデート ,IgG excretion rate ,vanadate ,アルブミン排泄率 ,ストレプトゾトシン糖尿病 ,腎肥大 ,renal hypertrophy - Abstract
Vanadate of a trace element has been shown to have insulin-like effects. The effect of vanadate on some parameters of renal function was studied on streptozotocin-induced diabetic rats with heminephrectomy. Rats were divided into four groups as follows: vanadate (v)-untreated normal rats, v-treated normal rats, v-untreated diabetic rats and v-treated diabetic rats. Oral administration of vanadate was started three weeks after the induction of diabetes and continued for a period of 10 weeks. The v-treated diabetic rats were characterized by significant (p
- Published
- 1993