1. [Stereocontrolled Total Synthesis of Biologically Active Natural Products].
- Author
-
Hatakeyama S
- Subjects
- Alkenes chemical synthesis, Alkenes chemistry, Aminoglycosides chemical synthesis, Aminoglycosides chemistry, Benzene Derivatives chemical synthesis, Benzene Derivatives chemistry, Biological Products chemistry, Indole Alkaloids chemical synthesis, Indole Alkaloids chemistry, Lactones chemical synthesis, Lactones chemistry, Macrolides chemical synthesis, Macrolides chemistry, Molecular Conformation, Sesquiterpenes, Guaiane chemical synthesis, Sesquiterpenes, Guaiane chemistry, Stereoisomerism, Biological Products chemical synthesis
- Abstract
This review article describes the total syntheses of englerin A, ophiodilactones A and B, marinomycin A, N-methylwelwitindolinone C isothiocyanate, tirandamycins A-D, and tirandalydigin, which possess intriguing biological activities and challenging structures with characteristic ring systems. The focus is on the synthetic methodologies that lead to the highly stereocontrolled assembly of these natural products.
- Published
- 2018
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