1. [Diffuse large B-cell lymphoma with intravascular involvement of neoplastic CD5-positive cells].
- Author
-
Matsuoka N, Sano N, Murayama T, Ueda K, Hashimoto H, Inoki T, Hirokawa Y, Yamaguchi M, and Katayama N
- Subjects
- Aged, Biopsy, Humans, Liver Neoplasms metabolism, Lymphoma, Large B-Cell, Diffuse metabolism, Male, Blood Vessels pathology, Bone Marrow pathology, CD5 Antigens metabolism, Liver Neoplasms pathology, Lymphoma, Large B-Cell, Diffuse pathology
- Abstract
A 77-year-old man was admitted because of fever. A small number of large CD20-positive neoplastic cells were seen in the bone marrow specimen. Clinical symptoms improved with oral prednisolone. After 11 months, abdominal CT scan revealed a liver mass. The biopsy specimen from the liver mass showed diffuse infiltration of large CD20-positive neoplastic cells. The patient was diagnosed as having diffuse large B-cell lymphoma. It was of particular interest that only neoplastic B cells within small blood vessels in the liver mass were positive for CD5. The patient died of lymphoma three months after diagnosis.
- Published
- 2013