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Start Over Descriptor "Carcinoid Tumor immunology" Language japanese
1 results on '"Carcinoid Tumor immunology"'

1. [Cytotoxic activity of large granular lymphocytes (LGL) infiltrated into metastatic tumors of lung cancer].

Author

Aoyagi Y, Takai K, Shibata A, Ishikawa H, and Ohnishi Y

Subjects
Carcinoid Tumor drug therapy, Carcinoid Tumor pathology, Female, Humans, Lung Neoplasms drug therapy, Lung Neoplasms pathology, Lymphatic Metastasis, Middle Aged, Picibanil therapeutic use, Antibody-Dependent Cell Cytotoxicity, Carcinoid Tumor immunology, Killer Cells, Natural immunology, Lung Neoplasms immunology
Abstract

Large granular lymphocytes (LGL) showing Leu 7 and weak E rosettes were separated from two metastatic tumors of lung cancer. Weak cytotoxic activity of these cells was recognized against autochthonous tumors, but never against K-562 cells. After OK-432 therapy, this cytotoxicity was not enhanced, but antibody dependent cell-mediated cytotoxicity (ADCC) of peripheral blood mononuclear cells of the patient was induced against metastatic tumors. These signs may suggest that specific immunotherapy should be available for these cancers.

Published
1984

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