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A 79-year-old woman was admitted to our hospital because of prolonged impaired consciousness and right hemiparesis. She was treated for acute cerebral infarction because her brain magnetic resonance imaging showed extensive cortical lesions similar to acute infarction in diffusion weighted image, fluid attenuated inversion recovery, and T2 weighted images. On the fifth day, she had a focal seizure on the right side. A new lesion during imaging and electroencephalogram abnormality were observed at that time. After the antiepileptic drug treatment was started, her right hemiparesis considered as ictal paresis, confusion, and the magnetic resonance imaging findings gradually improved. There was also an old, irreversible lesion in the left hippocampus, which was considered as the focus of her complex partial seizure. In the elderly, the post-ictal period of confusion, which occurs with complex partial seizure, may be prolonged. In our case, improvement of hemiparesis and confusion occurred after about 2 weeks.

We experienced the case that used S-1 for small intestinal cancer with peritoneal dissemination. A 51-year-old man admitted for fatigability and anemia. Small bowel series showed a stenosis lesion at the 15cm anal side from Treiz ligament, and the oral intestinal dilatasion was shown. CT showed the thickening of small intestinal wall and rectal wall. In addition, a rectal stenosis was shown by barium enema. It was diagnosed as small intestinal cancer with peritoneal dissemination, and an operation was performed. Peritoneal dissemination was recognized in the intraperitoneal whole, so jejunum partial resection was performed for primary cancer lesion. After an operation, internal use of S-1 was performed in an outpatient department. One course was assumed administration for four weeks and withdrawal for two weeks, and three courses was performed. There was not a side effect, and barium enema showed improvement of a rectal stenosis, and CT showed improvement of thickening of a rectal wall. A lesion worsened afterwards, and he died in postoperative six months.