1. [Human herpesvirus-6 and human herpesvirus-7 (HHV-6, HHV-7)].
- Author
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Tang H, Sadaoka T, and Mori Y
- Subjects
- Adult, Gene Expression Regulation, Viral, Genes, Viral genetics, Genome, Viral genetics, Humans, Immunity, Cellular, Immunity, Humoral, Infant, Membrane Cofactor Protein physiology, Receptors, Virus physiology, T-Lymphocytes virology, Virion pathogenicity, Virus Activation, Virus Integration, Virus Latency, Exanthema Subitum diagnosis, Exanthema Subitum therapy, Exanthema Subitum transmission, Exanthema Subitum virology, Herpesvirus 6, Human genetics, Herpesvirus 6, Human immunology, Herpesvirus 6, Human pathogenicity, Herpesvirus 6, Human physiology, Herpesvirus 7, Human genetics, Herpesvirus 7, Human immunology, Herpesvirus 7, Human pathogenicity, Herpesvirus 7, Human physiology
- Abstract
human herpesvirus 6 (HHV-6) is the major causative agent of exanthem subitum which is one of popular diseases in infant, and establishes latent infections in adults of more than 90%. Recently, the encephalitis caused by reactivated- HHV-6 has been shown in patients after transplantation. In addition, the relationship HHV-6 and drug-induced hypersensitivity syndrome has also been reported. human herpesvirus 7 (HHV-7) was isolated from the stimulated-peripheral blood lymphocytes of a healthy individual, and also causes exanthema subitum. Both viruses are related viruses which belong to betaherpesvirus subfamily, and replicate and produce progeny viruses in T cells.
- Published
- 2010
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