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Your search keyword '"Hayashi, Shunsuke"' showing total 12 results
Start Over Author "Hayashi, Shunsuke" Language japanese
12 results on '"Hayashi, Shunsuke"'

1. 線形半無限計画問題に対する切除平面法の高速化 (高度情報化社会に向けた数理最適化の新潮流)

Author

Hikima, Yasunari and Hayashi, Shunsuke

Abstract

線形半無限計画問題(LSIP)とは, 有限次元の変数をもつ線形関数を, 無限個の線形不等式で表される制約領域上で最小化する問題であり, フィルタ設計や汚染費用問題など多くの応用が知られている. LSIPに対する解法アルゴリズムとして切除平面法が知られているが, この手法では毎回の反復で生成される部分問題を厳密に解くことが前提となっている. そこで, 本稿ではこの部分問題を非厳密に解くことによって切除平面法を高速化するアプローチを提案し, アルゴリズムの収束解析を行う. 数値実験ではテスト問題に対して提案した高速化アプローチを適用し, 特に高次元の問題に対して, 提案アプローチの方が既存の切除平面法よりも高速に解が得られることを確認する.

Published
2019

3. The effect of dynamic visual noise on brain hemodynamic response during concrete word production task <Article>

Author

Takamura, Masahiro, Nishimoto, Mika, Hayashi, Shunsuke, Yamamoto, Fumie, and Miyatani, Makoto

Subjects
具象性効果, 近赤外分光法(NIRS), 単語産出課題, 二重課題法
Abstract

二重課題法や脳活動測定などの手法を用いた先行研究から,具象単語の意味処理に視覚イメージ処理が関与することが示唆されている。しかし,これまでの研究では主に単語の意味判断課題や記憶課題が用いられ、単語産出課題を用いた詳細な検討は行われていない。本研究では,具象単語の産出数や産出時の脳活動に視覚妨害課題が及ぼす影響を調べ,具象単語産出における視覚イメージ処理の関与を検討した。10名の成人女性に単語産出課題を実施し,近赤外分光法で課題遂行中の脳血流反応を記録した。単語産出課題は,単語の種類(具象・抽象)×視覚妨害(あり・なし)の4条件で行った。結果,単品産出数には視覚妨害の影響はみられず,具象単語がより多く産出された。脳血流反応では,具象単語条件において左前頭で有意な視覚妨害の効果がみられた。抽象単語条件では有意な視覚妨害の効果はみられなかった。この結果は,具象単語の産出に視覚処理が関与することを示唆する。

Published
2014

10. [Usefulness of subarachnoid phenol-glycerin block therapy for enabling cancer patients with refractory anal pain to proceed to home-based care].

Author

Hayashi S, Inoue D, Sakuyama T, Tanifuji Y, Moriya K, and Kawakubo T

Subjects
Aged, Anus Diseases etiology, Female, Glycerol therapeutic use, Humans, Male, Pain, Intractable etiology, Subarachnoid Space drug effects, Anus Diseases drug therapy, Glycerol analogs & derivatives, Home Care Services, Neoplasms complications, Neoplasms therapy, Pain, Intractable drug therapy
Abstract

In recent years, the number of cancer patients and their families desiring palliative home-based care in Japan has increased. Subarachnoid phenol-glycerin block therapy is offered to relieve refractory anal pain in cancer patients, and to reduce the side effects of systemic administration of opioids, such as drowsiness. The effects of phenol-glycerin, which is a medicine used for neurodegenerative diseases, lasted for 1 week to 3 months. Eight patients with this manipulation showed a significant improvement in their pain level, calculated by the numerical rating scale(NRS). Five of these patients could proceed to homebased care. It is important to establish common guidelines for the management of phenol-glycerin. The participation of pharmacists in the palliative care team will contribute to further growth of home-based care.

Published
2012

11. [Study of MDA-LDL by pioglitazone and pitavastatin in patients with type 2 diabetes].

Author

Taguchi A and Hayashi S

Subjects
Aged, Arteriosclerosis etiology, Arteriosclerosis prevention & control, Biomarkers blood, Coronary Artery Disease etiology, Coronary Artery Disease prevention & control, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 diagnosis, Disease Progression, Dyslipidemias complications, Dyslipidemias diagnosis, Female, Humans, Lipoproteins, LDL, Male, Middle Aged, Oxidative Stress, Pioglitazone, Risk Factors, Cholesterol, LDL blood, Diabetes Mellitus, Type 2 drug therapy, Dyslipidemias drug therapy, Hydroxymethylglutaryl-CoA Reductase Inhibitors administration & dosage, Hypoglycemic Agents administration & dosage, Malondialdehyde blood, Quinolines administration & dosage, Thiazolidinediones administration & dosage
Abstract

Oxidized LDL accelerates vascular endothelial damage and the progression of early arteriosclerosis, and is known as an independent risk factor for coronary artery disease. In this study, we administered pioglitazone and pitavastatin for 16 weeks to 18 patients who had type 2 diabetes complicated by dyslipidemia and then investigated the influence of these 2 drugs on MDA-LDL(i. e., oxidized LDL). As a result, a significant decrease of MDA-LDL was observed in both groups, but a significant decrease of the MDA-LDL/LDL-C ratio (an indicator of the extent of oxidation of LDL) was only observed in the pioglitazone group. Accordingly, it was demonstrated that pioglitazone improves oxidative stress, and the possibility was suggested that the MDA-LDL/LDL-C ratio is useful for the evaluation of oxidative stress in clinical practice.

Published
2011

12. [Sensitization of cough sensitivity through activation of C-and/or Adelta fibers].

Author

Kamei J, Hayashi S, and Ohsawa M

Subjects
Adenosine Triphosphate physiology, Animals, Antitussive Agents, Arachidonic Acids metabolism, Cyclin-Dependent Kinase 5 physiology, Drug Design, Endocannabinoids, Humans, Nerve Fibers, Unmyelinated metabolism, Nitric Oxide physiology, Polyunsaturated Alkamides metabolism, Prostaglandin-Endoperoxide Synthases physiology, TRPV Cation Channels physiology, Tachykinins metabolism, Tachykinins physiology, Cough etiology, Nerve Fibers, Myelinated physiology, Nerve Fibers, Unmyelinated physiology
Published
2008

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