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Hepatic aneurysms are rare, but can prove fatal once they rupture. Transcatheter arterial embolization (TAE) is performed as a prophylactic treatment. The position of the aneurysm determines the degree of difficulty of TAE. Maintaining blood flow to the liver can become difficult, particularly when the aneurysm is at an arterial junction. The patient was a 72-year-old man diagnosed with a hepatic aneurysm. The aneurysm was situated on the common hepatic artery at the junction of the gastroduodenal and proper hepatic arteries. TAE was performed with framing, followed by coil embolization. Blood flow to the liver was maintained via the gastroduodenal artery. Appropriate framing is important for safe and efficient TAE.

Dehydrative glycosidation reactions reported by the authors' group are reviewed. The authors' efforts were concentrated on developing reagent systems usable for one-stage-one-pot glycosidation. Such systems could simplify the glycosidation step using 1-OH sugar derivatives, since any preactivation stage for the hemiacetal OH group could be omitted. The systems, utilizing the dehydration potential of sulfonyl chloride, such as the p-nitrobenzenesulfonyl chloride-silver trifluoromethanesulfonate-triethylamine system as well as the p-nitrobenzenesulfonyl chloride-silver trifluoromethanesulfonate-N,N-dimethylacetamide-triethylamine system, were useful for the syntheses of many kinds of oligosaccharides. As a system free from any metals, the authors developed the trimethylsilyl trifluoromethanesulfonate-pyridine (TP) system. During the study of the system containing cobalt (II) bromide, the authors found that the bromide converts 1-OH sugar into the corresponding 1-Br derivative, which is then activated with the cobalt salt to undergo glycosidation with alcohol. To prepare partially benzylated sugar derivatives used as acceptors in the authors' studies, controlled benzylation and forced tritylation were carried out. Short syntheses of a variety of useful sugar derivatives using such convenient procedures are described. As a novel protecting group for the hemiacetal OH group, the authors used the 2-methoxyethyl group. Many kinds of trehalose-type disaccarides we prepared.

A 51-year-old woman was diagnosed as Crow-Fukase syndrome on July 1997, presenting with lymph node swelling, polyneuropathy, hepatomegaly, hypothyroidism, renal dysfunction, edema and skin change. Lymph node swelling and polyneuropathy improved in some degree after chemotherapy. She was admitted to our hospital on march 6, 1998 because of consciousness disturbance, right hemiparesis and non-fluent aphasia after fever and hypotension. The next day of admission, consciousness disturbance, right hemiparesis and non-fluent aphasia disappeared. MR images of the brain revealed low intensity on a T1-weighted image and high intensity on a T2-weighted image in the left parietal lobe. Furthermore, MR images also revealed diffuse hypertrophic dura matter with enhancement by Gd-DTPA, which made the diagnosis of chronic cranial pachymeningitis. The cerebral angiographies showed bilateral internal carotid artery occlusion. The cerebrospinal fluid showed normal cell count, total protein level of 82 mg/dl, and IgG level of 18 mg/dl. Since there has been very few case reports describing intimate relationship between Crow-Fukase syndrome and pachymeningitis, and between carotid occlusion and pachymeningitis, we speculated that the pachymeningitis might be associated with Crow-Fukase syndrome. Furthermore, pachymeningitis might be a cause of her bilateral carotid occlusion. The number of cases of Crow-Fukase syndrome associated with cerebrovascular disease was very rare. This is the first case which had bilateral internal carotid artery occlusion probably caused by chronic cranial pachymeningitis. Therefore, it is necessary to pay attention to cerebrovascular disease when the patient of Crow-Fukase syndrome is associated with pachymeningitis.