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It is thought that there is no effective traditional antibiotic therapy for MDRP, and a prevention of its transmission is the most important strategy for controlling infection. In practicing standard precautions for MDRP patients at home, we noticed some sort of anxiety and confusion among the healthcare workers and family caregivers. We made our experimental manual and unified our procedures for MDRP carriers at home to reduce such problems. Consequently, healthcare workers' stress was alleviated and the teamwork could be enhanced better. We think that it is significant to make a common manual for MDRP control to improve mutual understandings and to have a better cooperation among the concerned home care workers.