1. Long-Term Outcomes of Congenital Adrenal Hyperplasia
- Author
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Anna Nordenström, Svetlana Lajic, and Henrik Falhammar
- Subjects
cardiovascular diseases ,bone fracture ,mental disorders ,neoplasms ,mortality ,fertility ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
A plethora of negative long-term outcomes have been associated with congenital adrenal hyperplasia (CAH). The causes are multiple and involve supra-physiological gluco- and mineralocorticoid replacement, excess adrenal androgens both intrauterine and postnatal, elevated steroid precursor and adrenocorticotropic hormone levels, living with a congenital condition as well as the proximity of the cytochrome P450 family 21 subfamily A member 2 (CYP21A2) gene to other genes. This review aims to discuss the different long-term outcomes of CAH.
- Published
- 2022
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