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SUMMARY The aim of study was to determine the trends of mortality from external causes and suicides in Lithuania and other EU (European Union) countries in 1996-2006, using advanced trend analysis methods. Methods. Study design – descriptive epidemiology. Mortality from all external causes (by ICD-10 coding V01-Y98) and from suicides (by ICD-10 coding X60-X84) was analyzed in eighteen EU countries. It was used midyear of every countries population, numbers of deaths from external causes and from suicides based on five-year age groups, which totaled to 324 groups. Age-standardized (European standard population) mortality rates (per 100 000 persons) from causes mentioned above was calculated calculated using direct method. These standardized values were used to determine the trends, comparisons with other countries was made. MICROSOFT EXCEL 2003, WINPEPI module Describe (v. 1.78), JOINPOINT (v. 3.2.0), Harward Graphics 98 (v. 6.50), MAP WIEVER (v. 5.00) statistical packages and programmes were used for data processing and analysis. The following indices was calculated: standardized mortality rates, weighted standard error (SE), annual absolute change (AAC), annual percentage change (APC), 95% confidence intervals, data considered significant, when p