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Background Hypertension is an important health problem and one of the most important causes of disability and mortality. Objective This study aims to evaluate the effect of an educational program based on the Theory of Planned Behavior (TPB) on self-care behaviors in hypertensive patients. Materials and Methods This is a clinical trial conducted on 180 patients with hypertension referred to health centers in Rasht, Iran in 2014. They were divided into two intervention (n=75) and control (n=75) groups. Data collection tools included a demographic form, the Global Physical Activity Questionnaire, the Food Frequency Questionnaire, and a TPB questionnaire with five constructs including attitude, subjective norms, perceived behavior control, and behavioral intention related to hypertension. Collected data were analyzed in SPSS v. 18 software using descriptive and inferential statistics. Results Before intervention, two groups were similar in terms of the scores TPB constructs. After intervention, the mean scores of attitude changed from 4.51 to 4.58; mean scores of subjective norms changed from 4.16 to 4.19; mean scores of perceived behavior control changed from 3.64 to 4.23; and mean scores of behavioral intention changed from 3.88 to 4.24. These differences were statistically significant (P<0.05). No difference was observed in the control group. Conclusion An educational program based on TPB can promote the self-care behaviors among hypertensive patients. [ABSTRACT FROM AUTHOR]

In this study, cobalt ferrite nanomaterial with inverse spinel structure was synthesized via a co-precipitation method using Co(NO3)3.6H2O and Fe(NO3)3.9H2O. A 15% NH4OH solution was used as an alkaline agent for pH adjustment. Oleic acid was used as a coating agent on the surface of the synthesized cobalt ferrite nanoparticles. PXRD analysis confirmed that the obtained material had a main CoFe2O4 cubic crystal structure with space group Fd-3m and lattice parameters a=b=c= 8.40 Å (JCPDS standard card no = 01-077-0426). According to the SEM analysis, the pseudo-spherical particles size distribution and morphology of the assynthesized nanomaterial were homogeneous. The magnetic behavior of the obtained material was analyzed by vibrating-sample magnetometer (VSM). Besides, anticancer effect of the as-synthesized cobalt ferrite nanoparticles was examined on an experimental model of acute myeloid leukemia (CML) K562 cell line for the first time. Inhibition of cell growth and cytotoxicity (apoptosis) that are characteristics features of cobalt ferrite nanoparticles are tested on K562 cell line. The results showed growth and viability inhibition and induction of apoptosis in K562 cells treated with the nanoparticles. [ABSTRACT FROM AUTHOR]