1. Investigating The Relationship Between Personality Traits and Iron Overload in Transfusion-Dependent Thalassemia Patients
- Author
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M Rezapour, R Bagherzadeh ledari, R Ghorkhanechi, S Ahmad abadi, and M Naderisorki
- Subjects
thalassemia ,iron overload ,personality trait ,Medicine (General) ,R5-920 - Abstract
Background & aim: Thalassemia is the most common hereditary blood disease, and patients with thalassemia major need continuous blood transfusions to survive. Continuous blood transfusion in these patients is associated with iron. Therefore, the purpose of the present study was to investigate the relationship between personality traits and iron overload in these patients. Methods: The present descriptive-cross-sectional study was conducted on 150 thalassemia patients who were dependent on blood transfusion in the thalassemia department of Bu Ali Sina Hospital in Sari in 2021. The clinical and laboratory information of the patients were collected using the medical record. At that point, the patients answered the 5-factor neo personality questionnaire, which is a 60-question questionnaire. To analyze the collected data, descriptive statistics such as mean and standard deviation were used in case of normal distribution of the main outcome, and median and IQR indices were used otherwise. Results: The results indicated that the personality characteristic of conscientiousness was more in people with regular visits than in people with irregular visits (P=0.021). In the study of the relationship between liver iron overload and the regularity of visits, it was perceived that iron overload had a significant relationship with the regularity of visits (P=0.018), so that moderate and severe iron overload was more in people who had irregular visits. But cardiac iron overload had no significant relationship with regular visits (P=0.910). The use of chelators had a significant relationship with the characteristic of neurosis (P=0.021), so that the score of neurosis in patients who took chelators was higher than those who did not use chelators. Conclusion: The findings of the present study indicated that there was no significant relationship between any of the personality traits with iron overload in patients with transfusion-dependent thalassemia, except for conscientiousness, which was more in people with regular visits than in people with irregular visits.
- Published
- 2024