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Your search keyword '"Safarian S"' showing total 2 results
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2 results on '"Safarian S"'

1. Study of the Effects of Acetazolamide on Decreasing Viability of Breast Cancer Cells in T-47D Cell Line

Author

Abdolmohammadi M.H, Ejheian F, Safarian S, and Mohammadpour R

Subjects
Acetazolamide, Breast Neoplasms, Apoptosis, Cell Cycle, Flow Cytometry, Medicine (General), R5-920
Abstract

Background and Objectives: This study aimed at investigating the inhibitory effect of acetazolamide on the growth and proliferation of breast cancer cells (T47-D).Methods: The appearance of morphological symptoms of apoptosis was checked after staining with Annexin-PI using fluorescent microscope. Flow cytometric studies were used for determination of the amount and type of cellular death and also for analyzing the cell division cycle. The amounts of caspase-3 activity and DNA laddering were determined in the treated cells and compared with samples of the control group. Unilateral variance test was used to analyze data (p

Published
2011

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