Descriptor: "Amoxicillin analysis" / Language: polish - Searchworks@Jio Institute Digital Library Search Results

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Start Over Descriptor "Amoxicillin analysis" Language polish

Author: Pajchel G, Borowiecka B, and Chojnowski W
Subjects: Anti-Bacterial Agents analysis, Drug Combinations, Hydrolysis, Amoxicillin analysis, Clavulanic Acid analysis, Colorimetry methods, Spectrophotometry methods
Abstract: The spectrophotometric method for determination of clavulanic acid and amoxycillin after NaOH hydrolysis was elaborated.
Published: 1992

Author: Płotkowiak Z and Nogowska M
Subjects: Amoxicillin analysis, Drug Stability, Amoxicillin pharmacology, Hot Temperature, Humidity
Abstract: Dependence of stability of Amoxycillin trihydrate (AMOXY. 3H2O) and Amoxycillin-Natrium (AMOXY-Na) upon relative humidity (RH) and temperature was investigated using the iodometric method for the determination of Amoxycillin. The first order rate constants and activation parameters have been determined at controlled moisture conditions. The straightline relationship lg k = f(RH) at T = const. has been stated, which however is fulfilled by AMOXY-Na only at RH greater than or equal to 50%. The calculated factors of the equation lg k = a + b.1/T + c.RH proved to enable estimation of the stability of the studied antibiotics at any climate conditions. The performed kinetic studies have shown that AMOXY-Na undergoes degradation about 1.5 x 10(3) times faster than AMOXY.3H2O, at RH greater than or equal to 50%.
Published: 1989

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