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We report a 17-year old girl, with severe aplastic anaemia (SAA)and juvenile fibroadenoma. She was treated with immunoablative therapy (IST), due to lack of a family bone marrow donor. She did not respond to the first course of IST. We administered second course of IST (ATG+CSA), because there was also no unrelated bone marrow donor. In January 2007 (1 year after starting CSA treatment), a palpable mass was found in the left breast.USG examination, performed after 2 months of observation, confirmed the presence of numerous lesions in the left and right breast (suggested fibroadenoma). Diagnostic biopsy was not performed due to high risk of bleeding. During a two step operation the biggest lesions were excised. Histopathological examination confirmed the diagnosis juvenile fibroadenoma of on physical examination, 8 months after the operation, there are again palpable nodular lesions in the left breast. (USG suggests fibroadenoma) The girl remains under systematic control. Now she has partially responded after second course of IST. Juvenile fibroadenoma of the breast in our patient may be a side effect of CSA therapy (she was treated with CSA for 2 years).

A 14-year old girl was admitted to the Department of Paediatric Surgery of the Regional Health Centre in Opole with 4-month lasting history of increasing enlargement of the left breast. Sonography revealed a not infiltrative tumour located in the left breast; fin e needle aspiration did not evidence any malignant cells. In consequence, marginal excision of this encapsulated tumour was performed. Final histopathological examination established the diagnosis of the "juvenile fibroadenoma of breast". The postoperative period was uneventful, and the cosmetic was accepted by the patient. The rarity of malignant tumours of breast in adolescents do not exclude such possibility, however it needs careful diagnostics and conservative approach to exclude malignancy. It seems important to perform an immediate plastic repair of correction alter surgical resection of the tumour.

Maffucci's syndrome is a rare nonhereditary malformation of mesodremal dysplasia origin which consists of multiple hemangiomas of the soft tissue and multiple enchondromas. Only approximately 170 cases of this disease have been reported in the literature. Maffucci's syndrome is known to be associated with tumors of mesodermal origin. Chondrosarcoma, osteosarcoma and angiosarcoma are the most common malignant neoplasms and the benign tumors consist of pituitary adenoma, adrenal cortical adenoma, parathyroid adenoma, thyroid adenoma and breast fibroadenoma. We present a case report of a 26-year old female patient with Maffucci's syndrome and a giant thorax tumor composed of fibroadenoma and canalicular adenoma.