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The viscosity of whole blood taken from patients suffering from different diseases was studied. The measurements of blood viscosity were performed in the shear rate range 0.01-100 s-1 in three groups of patients. The first group consisted of 60 patients without known cardiovascular disorders referred for a non-vascular minor surgery (patients did not take any drugs influencing vascular system). The second group (30 persons) consisted of patients after cerebral ischemic episode, remaining under permanent medical control. The third group consisted of 100 patients after myocardial infarction. In the group of patients suffering from vascular system disorders (second and third) the blood viscosity has been significantly lower then in the first group. Such results might suggest that in patients with vascular system disorders blood viscosity has been decreased in the way of specific feedback mechanism, whereas the beneficial hemorrheological influence of secondary prevention seems to be questionable.

Objectives: In the present study fetal right coronary artery blood flow velocimetry was assessed., Design: The prognostic value of the fetal right coronary artery blood flow velocimetry was evaluated in relationship with parameters of newborn's condition after birth., Material and Methods: The study was performed in 102 cases of pregnancies complicated by pregnancy induced hypertension. Blood flow velocimetry was visualized from fetal right coronary artery and correlated with perinatal outcome parameters., Results: Fetal coronary blood flow velocimetry was visualized only in 11 cases. Coronary blood flow velocimetry visualisation correlated with each parameter of after-birth evaluation. The method has the highest specificity (97.7%) and positive prognostic value (85%) concerning evaluation of newborn's condition., Conclusions: Fetal right coronary artery blood flow velocimetry visualisation is a late sign of chronic fetal hypoxia. This seems to be a factor which causes maximal coronary vessels dilatation and allows oxygenation of fetal heart muscle.

In this paper the stages and pathogenesis of diabetic nephropathy have been presented. Factors which influence blood rheology and hemorheologic abnormalities founded in diabetic patients have been reviewed. Attention was paid to the role of rheological parameters in initiating and progression of diabetic nephropathy. The possibilities of prevention of diabetic microvascular complications by influencing blood rheology have been presented.