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Introduction: Esophageal electric impedance combined with pH-metry (MII-pH) is becoming the standard in the diagnosis of gastroesophageal reflux disease (GERD). The ability to detect reflux episodes and analyze their chemical and physical proprieties renders this test valuable. Aim of the study: Assessment of the diagnostic value of multichannel intraluminal impedance with pH-metry in the diagnosis of gastroesophageal reflux disease, as compared to pH-metry, assessment of the correlations between symptoms reported and recorded episodes of pathological reflux episodes, based on our own studies. Materials and methods: The study group comprised 90 children aged 3 months to 17 years (average age 11.85) suspected of gastroesophageal reflux disease. We performed examination using multichannel intraluminal impedance probe with pH-metry option appropriate for the child's age. Sandhill Scientific software was used for data analysis with subsequent independent analysis of impedance and pH-metry and both together. Results: Basing on our examination, we have diagnosed pathological gastroesophageal reflux in 48 patients. Acid reflux was found in 31 patients. 15 patients had prolonged acid time in pH-metry, while impedance recording was normal. Nonacid reflux was found in 5 children and 12 patients have been diagnosed with mixed reflux. Conclusions: Esophageal electric impedance combined with pH-metry comprises a valuable tool for the diagnosis of pathological gastroesophageal reflux. MII-pH enables us to analyze not only chemical, but also physical proprieties of the refluxate and it is superior to pH-metry alone. [ABSTRACT FROM AUTHOR]

Unlabelled: The observed with age, atherosclerotic changes in vessels and increasing damage to the vascular endothelium, causing an increase in the occurrence of cardiovascular events. An important element in the rehabilitation of patients with coronary artery disease is a physical activity, to complement the pharmacological treatment., Aim: The aim of the study was to evaluate the influence of a controlled exercise training on changes in central and peripheral circulatory system in patients after acute coronary syndrome., Materials and Methods: Group comprising 92 patients were divided into three subgroups. The rehabilitation period ranged from 2 to 4 weeks. In group I and II performed a series of interval training on a bicycle ergometer supplemented by general conditioning exercises; in the group III training individually tailored program, consisting of breathing exercises, relaxation and small muscle groups. In all groups, before and after the training cycle test was performed impedance plethysmography of the chest, echocardiography, exercise test., Results: After completing the program, the parameters plethysmography improved in all groups, with the largest changes were observed in the group treated to the longest training: increase PAmpl (pulse wave amplitude) of 16.7% and PSlope (systolic slope) of 17.6%, while decline in the value of CT (crest time) by 5.7% and PT (propagation time) by 6.3%. In groups, which carried out a controlled exercise training have improved as well: exercise capacity of patients, stroke volume SV, cardiac output CO and global myocardial contractility EF. Moreover, a correlation between the results plethysmography parameters and SV, CO and EF., Conclusions: Controlled physical training, which comes under the standard procedure rehabilitation of patients after acute coronary syndrome, leads to better blood perfusion in vessels of the legs and improve myocardial functional parameters, thereby affecting the growth of physical capacity of patients., (© 2016 MEDPRESS.)