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6 results on '"Receptors, Steroid analysis"'

2. [Steroid hormonal receptors, heat shock protein and p53 of endometrioid and clear cell cancers in different localization].

Author

Kedzia W and Spaczyński M

Subjects
Adenocarcinoma, Clear Cell chemistry, Antibodies, Monoclonal, Endometrial Neoplasms chemistry, Female, Gene Expression Regulation, Neoplastic, HSP90 Heat-Shock Proteins immunology, Humans, Immunohistochemistry, Neoplasm Staging, Receptors, Estrogen analysis, Receptors, Progesterone analysis, Receptors, Steroid immunology, Tumor Suppressor Protein p53 immunology, Up-Regulation, Adenocarcinoma, Clear Cell pathology, Biomarkers, Tumor analysis, Endometrial Neoplasms pathology, HSP90 Heat-Shock Proteins analysis, Receptors, Steroid analysis, Tumor Suppressor Protein p53 analysis
Abstract

Objectives: Most endometrioid, well differentiated cancers are positive for ER and PgR., Materials and Methods: By using specific monoclonal antiER, PgR, p53 and hsp 90 antibodies, immunohistochemical reaction was used to study paraffin-embedded specimens from 53 patients with primary endometrioid and clear cell cancers., Results: Most carcinomas with p53 overexpression showed no reactivities of ER and PgR., Conclusions: Presence of p53 and absence of steroid hormone receptors suggest a poor clinical prognosis for patients with endometrioid and clear cell cancers.

Published
2002

3. [Receptors for biologically active substances in the light of the studies using monoclonal antibodies].

Author

Lipski S

Subjects
Humans, Models, Biological, Receptors, Cell Surface immunology, Receptors, Cell Surface isolation & purification, Receptors, Neurotransmitter analysis, Receptors, Neurotransmitter immunology, Receptors, Neurotransmitter isolation & purification, Receptors, Steroid analysis, Receptors, Steroid immunology, Receptors, Steroid isolation & purification, Antibodies, Anti-Idiotypic immunology, Antibodies, Monoclonal immunology, Receptors, Cell Surface analysis
Abstract

This paper presents a review of studies on the structure and function of receptors for biologically active substances (hormones, drugs etc.). Application of the methods utilizing monoclonal antibodies are described and discussed.

Published
1989

4. [Steroid hormone receptors; their appearance in breast cancer; usefulness of the findings in the selection of patients for endocrine therapy and prognosis of tumor development].

Author

Paszko Z, Padzik H, Pieńkowska F, Chrapusta S, Konopka B, and Peczko D

Subjects
Adult, Age Factors, Aged, Breast Neoplasms drug therapy, Estradiol Congeners therapeutic use, Female, Humans, Middle Aged, Neoplasm Regression, Spontaneous, Prognosis, Breast analysis, Breast Neoplasms analysis, Receptors, Steroid analysis
Published
1983

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