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The objective of the study was to evaluate the influence of a high voltage stimulation on the process of healing of crural ulcerations after causal surgical treatment. Two comparative groups of patients, A and B, were made at random from patients with venous crural ulcers, who had been earlier operated by Babcock' method. The group A consisted of 12, and the group B--13 patients. The patients in two comparative groups were treated pharmacologically. Ulcerations at the patients in the group A were additionally treated with the high voltage stimulation. Changes of the area, length, width, and volume of the tissue defect after the high voltage stimulation were assessed. Weekly changes of the above parameters were determined as well. After the therapy there was a statistically significant decrease of the total and pus-covered areas, length, width and volume of ulcerations in both groups, while there was no statistically significant difference--except pus-covered areas--between the groups observed. Only the reduction of pus-covered area in the group A was statistically significantly faster than in the group B.

The authors present a case of 75-year old female, who has suffered from venous insufficiency crural ulcerations and lost hope for any relief for 50 years. Hospitalisation for a femur fracture has been a turning point. The patient learnt that modern medicine can treat disease that she suffered from for most of her life.

We have included PGE-1 to the clinical management of varicose ulcers of the leg. We found the results very interesting and promising. The literature on using PGE-1 for this disease entity is rather poor and the biomechanics is still unclear.

The results of treatment of varicose crural ulcers are reported in a group of 85 patients. Cure was achieved in 75 cases. The social and economic aspects of this problem are stressed.