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At the end of 2019, in Wuhan, China, a coronavirus pandemic started, later called SARS CoV 2 and identified as the cause of CO VID 19 disease. This virus is a public health concern due to its ease of transmission. This virus is a public health concern due to its ease of transmission. One way to reduce this spread is by reinforcing biosafety care, therefore, this research aimed to describe the biosafety measures that should be adopted by laboratories to contain the new coronavirus in the workplace and also present the effective ways of inactivating the virus in clinical samples. For this, a bibliographic review was carried out in the online database of the Virtual Health Library (VHL), using the descriptors "Coronavirus Infections" or "Coronavirus Infections" and "Biosafety". After applying the inclusion and exclusion criteria, thirteen papers were used to write this material. Subsequently, biosafety measures against SARS CoV 2 were described, sectioned by: work team, personal protective equipment, laboratory environment, sample handling, sample processing and analysis, accidents and virus inactivation in samples. It can be concluded that it is essential for the laboratory team to know the principles of biosafety, in order to try to reduce the transmission of the new coronavirus, in addition to continuous training for professionals and the adoption of strict protocols and guidelines. [ABSTRACT FROM AUTHOR]