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Abstract Background Dermatomyositis (DM) is an infrequent disease subgroup of idiopathic inflammatory myopathies characterized by distinct skin lesions. However, high heterogeneity makes clinical diagnosis and treatment of DM very challenging. Objectives Unsupervised classification in DM patients and analysis of key factors related to clinical outcomes. Methods This retrospective study was conducted between 2017 and 2022 at the Department of Rheumatology, Xiangya Hospital, Central South University. 162 DM patients were enrolled for unsupervised hierarchical cluster analysis. In addition, we divided the clinical outcomes of DM patients into four subgroups: withdrawal, stabilization, aggravation, and death, and compared the clinical profiles amongst the subgroups. Results Out of 162 DM patients, three clusters were defined. Cluster 1 (n = 40) was mainly grouped by patients with prominent muscular involvement and mild Interstitial Lung Disease (ILD). Cluster 2 (n = 72) grouped patients with skin rash, anti-Melanoma Differentiation Associated protein 5 positive (anti-MDA5+), and Rapid Progressive Interstitial Lung Disease (RP-ILD). Cluster 3 (n = 50) grouped patients with the mildest symptoms. The proportion of death increased across the three clusters (cluster 3 < cluster 1 < cluster 2). Study limitations The number of cases was limited for the subsequent construction and validation of predictive models. We did not review all skin symptoms or pathological changes in detail. Conclusions We reclassified DM into three clusters with different risks for poor outcome based on diverse clinical profiles. Clinical serological testing and cluster analysis are necessary to help clinicians evaluate patients during follow-up and conduct phenotype-based personalized care in DM.

ABSTRACT The objective of this study was to assess the effect of Suanzaoren decoction on stress response of horses in transportation. A total of six male Ili horses were equally divided into Suanzaoren decoction treatment group (n = 3; basal diet supplemented with Suanzaoren decoction, three times/day) and control group (n = 3; basal diet, three times/day). After feeding for five days, all horses were transported for 8 h to simulate stress. Blood and serum samples were obtained before transport (BT), during transport (T), and after transport (AT). Results showed that there was significant interaction between road transport and dietary Suanzaoren decoction supplementation for the white blood cells (WBC), intermediate cell ratio (MID%), granulocyte ratio (GRAN%), alanine aminotransferase (ALT), glucose (GLU), aspartate transaminase (AST), creatine (CK), cortisol (COR), human growth hormone (HGH), adrenocorticotropic hormone (ACTH) and arginine vasopressin content, insulin (INS), and thyronine 4 (T4) in blood and serum. The highest WBC was found in T group. The highest GRAN%, ALT, GLU, AST, CK, T4, ACTH, and INS contents were observed in serum from AT groups, which was decreased by treatment. In conclusion, dietary Suanzaoren decoction supplementation did relieve horse transportation stress. This study provides a useful clinical therapy for relieving transportation stress of horses.

Abstract ASEAN has arguably been one of the most successful regionalisms, which since its inception has undergone several profound challenges, including the 1997 Asian financial crisis. In response to the fierce competition among major powers and the economic and social challenges, ASEAN has concentrated on sustainable development to promote unity and centrality. Sustainable development cooperation aligns with the interests of ASEAN states and helps to promote the construction of the ASEAN community and strike a balance of power on the world stage. Nevertheless, there may be a need for more efforts to resolve the challenges facing sustainable development.

The ternary amorphous CuSeP2 was designed and prepared as the anode material of potassium ion battery for the first time, and its electrochemical performance was also investigated. After ball-milling with commercial graphene powder, it is used as the anode material for potassium ion battery with reversible specific capacity up to 300 mAh g-1, and the corresponding initial coulombic efficiency is close to 60%. What’s more, the specific capacity remains above 150 mAh g-1 after 100 cycles at 200 mA g-1. When increasing the current density to 1000 mA g-1, the CuSeP2/graphene composites still has a potassium storage specific capacity of 100 mAh g-1. Our results show that the potassium storage mechanism of the ternary CuSeP2 anode material is a typical conversion reaction and the introduction of Cu can not only buffer the volume expansion during the subsequent electrochemical reaction, but also effectively enhance the electrochemical reversibility of potassium ion.

ABSTRACT This paper discusses the design of a safflower picking robot control system and focuses on a navigation control subsystem based on multisensor fusion. A navigation subsystem, an identification and positioning subsystem, a picking subsystem, and a levelling subsystem are designed. The hardware and software of the navigation subsystem are designed in detail, and a multisensor fusion positioning method based on extended Kalman fusion technology is proposed. The accuracy and stability levels of different combined navigation methods are compared. To test the effectiveness and accuracy of the proposed method, an outdoor test is carried out. The test results show that the outdoor fusion positioning accuracy of the robot is less than 8 cm, and when the satellite signal is lost, the navigation control subsystem can still provide high positioning accuracy. The final positioning result obtained using the integrated positioning method of the wheel odometer + IMU + DGNSS is approximately 52% higher than that of the odometer, approximately 29% higher than that of the wheel odometer + IMU, and approximately 11% higher than that of the IMU + DGNSS.

ABSTRACT Objectives: Investigate the effect of closed reduction and per- cutaneous pedicle screw fixation in treating thoracolumbar fractures. Methods: This retrospective study analyzed 12 cases of single-segment thoracolumbar spine fractures without spinal cord and nerve injury at our department from March 2016 to September 2017. Patients were treated with closed reduction, percutaneous reduction, and internal fixation with solid pedicle screws. The operation time, intraoperative blood loss, anterior vertebral body height ratio (AVHR), Cobb angle (CA) of sagittal kyphosis, and VAS of back pain were determined and statistically compared. Results: The average operation time was 147.2 ± 45.6 min, and the average intraoperative bleeding was 67.8 ± 34.2 mL. All fractured vertebrae were completely reduced, their height was restored, and kyphosis was corrected. The average follow-up period was 10.6 ± 2.7 months, with significant improvements seen in the AVHR, CA of sagittal kyphosis, and VAS score (P < 0.01). One case had a broken rod after three months, and another had a postoperative infection. All the patients achieved bony healing. Conclusion: The treatment of thoracolumbar fractures by closed reduction and internal fixation with a percutaneous solid pedicle screw is simple, effective, and economical. Level of Evidence VI; Therapeutic Study, Case Series.

ABSTRACT Objective: This study aimed to explore the clinical application of preoperative precise design for 3D printing and thumb reconstruction, which could help manage the patients with thumb defect and achieve better function and appearance. Methods: This was a retrospective study of 20 patients who underwent the surgery of harvesting toe transplant and thumb reconstruction between January 2015 and December 2016. The 3D model of the thumb defect was created and printed. The dimensions of skin and bones from donor site were precisely designed as reference for surgical operation. The surgery was performed according to the model. Results: Perfect repair of defects was achieved with satisfying appearance and function. The reconstructed thumbs all survived (survival rate of 100%). Follow-up was 3-9 months. The maximum dorsiflexion was 8-30° and the maximum flexion was 38-58°. The two-point sensory discrimination was 9-11 mm. In total, 17 patients reposted “Excellent” satisfaction and three “Good”, each for the reconstructed thumb and hand function, respectively. The satisfaction rate was 85%. Conclusion: Preoperative digital design and 3D printing according to the donor and recipient sites allowed a tailored operation. The operation was more precise, the appearance of the reconstructed thumb was good. Level of Evidence II, Retrospective Study.

Durante los últimos veinte años, el auge económico de China ha estado acompañado por mayores ambiciones y por una política exterior cada vez más asertiva. Estos factores han introducido numerosos elementos de innovación y cambio en los mercados, las instituciones y la gobernanza global. Las implicaciones de estas innovaciones para la región latinoamericana aún no se han apreciado por completo. Este dossier de la revista Razón Crítica, cuya edición es fruto de la cooperación académica entre la Universidad de Bogotá Jorge Tadeo Lozano (Colombia) y el Centro de Estudio de los los Países Hispánicos del Instituto de la Franja y la Ruta de la Universidad del Suroeste (Chongqing, China), está enfocado en destacar las características de este cambio más relevantes para América Latina. Al observar varias áreas como la política exterior, la política comercial, las relaciones entre el Estado y el mercado, las cadenas de valor globales, la reducción de pobreza, entre otros, los autores de los artículos presentados han demostrado que Beijing, a punto de convertirse en la economía más grande del mundo, ha desencadenado cambios que se desarrollan rápidamente en una variedad de esferas cruciales.

China ha alcanzado grandes logros en la reducción de pobreza y ha sido ampliamente reconocida por el mundo. Por el contrario, América Latina y Caribe (ALC) está atrapada en la pobreza; así, la cooperación entre ambas partes va a ser muy importante para alcanzar los objetivos de la Agenda del Desarrollo Sostenible de la onu para 2030. Con el fin de evaluar las colaboraciones enfocadas en la reducción de pobreza hechas por ambas partes, y mejorar el proceso con estrategias viables, este artículo se realiza de manera cualitativa a través de una amplia lectura. Asimismo, se divide en tres objetivos principales: describir la pobreza desde una dimensión múltiple de alc, definir las ventajas y desafíos de las cooperaciones desde el nivel macro, meso y micro, y diseñar estrategias de mejora para la colaboración, enfocadas en la reducción de la pobreza de ambas partes en el futuro. Se descubre que, durante los últimos 20[1] años, China y ALC han realizado una gran cantidad de colaboraciones en términos políticos, económicos, infraestructurales, culturales y otros más; además, la promoción del desarrollo económico ha ayudado a reducir la tasa de pobreza. Sin embargo, también dificultan el proceso los desafíos, la falta de mecanismos políticos específicos, la construcción de infraestructura que produce influencias negativas; en ese sentido, el comercio internacional debe ampliar tanto el volumen como el rango de productos, el intercambio cultural debe ampliar su cobertura, etc. Por último, bajo los cinco indicadores de la iniciativa de La Franja y la Ruta, el artículo plantea una serie de estrategias para el futuro. [1] El presente artículo se estructura como resultado parcial del proyecto aprobado, con el código 2021WYZX05, por Chongqing Federation of Social Science; el proyecto 2021JY077 por Southwest University of China y el proyecto SWU2109230 por Fundamental Research Funds for the Central Universities of China.

ABSTRACT To mitigate the large demand for safflower picking labour and the low efficiency of manual picking, a safflower picking robot that is based on a parallel manipulator is designed. The whole robot mainly consists of a walking device, parallel manipulator device, vision device, picking device, filament collection device, control system, and motor drive system. The forward and inverse kinematics analysis of the parallel manipulator is analysed via a geometric method, the kinematics model is established, and the computational analysis of the parallel manipulator working speed is based on the Jacobi matrix. For driving angle errors of 0.001∼0.005°, the moving platform's motion accuracy is 0.2174–0.9387 mm, which meets the position accuracy requirements of the test stage. Based on MATLAB software, the Monte Carlo method is employed to solve the working space of the parallel manipulator, which is approximately an equilateral triangle with a side length of 0.35 m, which satisfies the safflower growth space picking conditions. The prototype is constructed, and safflower picking experiments are carried out under laboratory conditions. The average picking period of each flower bulb was 16 s, and the average net picking rate of the filaments was 87.91%. The experimental results verified the applicability of the safflower picking robot.

Traditional martial art is a pivotal part of Chinese folk culture. However, due to the impact of modern culture, the inheritance of various martial arts is threatened. Therefore, many efforts have been made by the Chinese government to protect this unique culture in the late 20th century. To provide practical indications for the safeguard of intangible cultural heritage, we conducted a literature review for the Chinese strategies concerning the safeguard of traditional martial arts (TMA) in the past 30 years, also tried to identify the advantages and shortcomings of current safeguard of TMA. Existing evidence indicates that the legislative safeguarding of Chinese TMA has gradually evolved into a system for preservation. Modern devices are important to maintain the current form of the intangible cultural heritage. Inviting inheritors of the TMA to teach relevant skills and knowledge in university campuses may play an important role in the dynamic safeguard of inheritance. On the other hand, shortcomings are also noticed. For instance, younger generations are not fully aware of the importance of TMA, thus specific education is needed. The means of transmission of TMA is still insufficient in the current information era.

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