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The University-Business-Government cooperation, also known as triple-helix, has been identified as the most effective way to integrate the corporate and academic world, encouraging innovation projects that support regional technological development. Faced with the recent dismantling of the public funding system for academic research in Brazil, many Universities have advanced in their strategy of partnerships with companies, in the search for guaranteeing resources for the maintenance of their research activities. This paper seeks to discuss how these relationships have occurred in this scenario, through a theoretical and practical discussion, bringing the example of a case study carried out at the Technological Park of the University of Sorocaba, in the interior of the state of São Paulo. It was possible to show that the approach to the private sector is, above all, a survival strategy in the market for institutions that work with research. Amidst a political scenario that points to the retraction of the State's role as a provider of public resources for research, this apparently irreversible movement draws a new scenario for science and technology in the country, with the increasing presence of the private sector, which is leaving the role of client or demander of technologies and innovations generated in the predominantly public research infrastructure of the country, to occupy the leading role in technological development. A scenario that will continue to privilege only a few areas involved with issues of private interest, which are rapidly becoming issues of national interest, reducing the space for other areas of science, which will need to find their own way of survival. [ABSTRACT FROM AUTHOR]