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1. [Molecular characterization of HTLV-1 among patients with tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará].

Author

Souza LA, Lopes IG, Maia EL, Azevedo VN, Machado LF, Ishak MO, Ishak R, and Vallinoto AC

Subjects
Base Sequence, DNA, Viral analysis, Enzyme-Linked Immunosorbent Assay, Humans, Molecular Sequence Data, Paraparesis, Tropical Spastic diagnosis, Polymerase Chain Reaction, Human T-lymphotropic virus 1 genetics, Paraparesis, Tropical Spastic virology, Sequence Alignment
Abstract

The present study evaluated the occurrence of HTLV-1 and its subtypes in blood samples of patients presenting symptoms of tropical spastic paraparesis/HTLV-1 associated myelopathy. The detection of HTLV infection was performed by serological and molecular assays. Five patients were infected by HTLV-1 of the Cosmopolitan subtype, subgroup Transcontinental. The results confirm the occurrence of HTLV-1 infection among patients with clinical diagnosis of tropical spastic paraparesis/HTLV-1 associated myelopathy in Belém, Pará.

Published
2006
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