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We studied Bcl-2 proto-oncogene expression in dysplastic and malignant lesions of the uterine cervix and looked for a relation between its incidence and tumor histopathologic type and tumor differentiation grade. We used immunohistochemical reaction with a Bcl-2 specific monoclonal antibody in order to identify this protein in 40 patients' biopsies. We noticed a Bcl-2 nuclear immunoreaction in high differentiated squamous carcinomas, whereas a positive cytoplasmic reaction of a granular pattern was registered in low differentiated types. Distribution and intensity of Bcl-2 reaction final product was correlated with tumor differentiation grade in 29 of all studied cases (72.5%). Immunostaining technique may be an important adjuvant factor for a more accurate prognosis.

300 patients with benign prostatic hyperplasia admitted in hospital between 1994 and 1998 were studied. The surgical procedure in 21 patients was TUIP (transurethral incision of prostate), in 18 patients was classic adenomectomy (open prostatectomy), in 58 patients classic TURP (transurethral resection of prostate) and in 203 patients TURP by low pressure (hypopressure). The immediate complications in those patients who underwent endoscopic procedures were bleeding in 18 patients, acute urinary infections in 20 patients, endotoxic shock in 5 patients, epididimytis in 9 patients, urine retention in 4 patients, obstruction of catheters in 10 patients, collection of washing liquid in perivesical space (Retzius) in 3 patients. The late complications were the following: bleeding--4 cases, imperative micturition--12 cases, vesicle neck sclerosis--3 cases, urethral orifice stenosis--16 cases, urethral stricture--3 cases, urinary retention--6 cases, abscess in perivesical space (Retzius)--1 case. After TURP in hypopressure, the complications were less frequent due to a better visualization a more rapid execution of the procedure.

The authors have studied 30 patients with transient global amnesia aged between 49 and 76 years (median age of 63 years), without focal neurologic signs that have been followed for periods varying between 6 months and 10 years. Three of the patients had recurrent attacks of transient global amnesia, and another three had a stroke, although at some distance from the amnesia attack. Association was noted with certain risk factors including high blood pressure, and angiopathic changes of the eye fundus (in 50% of the patients), dyslipidemia (in 30%), diabetes (in 10%), and essential polyglobulia (in 7%). Coagulation studies including thrombelastograms were carried out in 22 patients, and demonstrated hypercoagulability in 50% of them. Changes in the arterial wall were noted in 85% of the 14 patients in whom carotid sphygmograms were recorded. The presence of these risk factors could explain the occurrence of cerebrovascular accidents in patients with transient global amnesia. Electroencephalograms performed immediately or a short time after the amnesia attack have evidenced in 18 patients rapid-type dysrhythmia, or diffuse theta waves, predominantly located in the deep layers of the left and right temporal areas. The EEG tracings were either flat or normal in the remaining 12 patients. Of the 30 patients presenting with global transient amnesia only two had migraine in antecedents, and another six had headache during the evolution of amnesia. The neurologic examination did not reveal any abnormality in 27 of the patients. Sequelar signs of neurological deficits were noted in the remaining three patients.(ABSTRACT TRUNCATED AT 250 WORDS)