1. [Corticotherapy in aggressive chronic hepatitis (ACH)]
- Author
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D, Dobre, G, Datcu, S, Botezatu, I, Bostaca, O, Cioară, M, Caţăr, and F, Curic
- Subjects
Hepatitis B, Chronic ,Treatment Outcome ,Dose-Response Relationship, Drug ,Biopsy ,Disease Progression ,Humans ,Prednisone ,gamma-Globulins ,Glucocorticoids ,Biomarkers ,Retrospective Studies - Abstract
48 patients with the diagnosis of ACH, admitted in the interval 1972-1981 and subjuected to corticotherapy were investigated by hepatic puncture biopsy with Vim-Silverman needls. The dose of prednison was of 15-20 mg daily for 2-4 years, with a mean 20 months. Corticotherapy was efficient in 73% of the cases, stabilization of the clinical and hepatic functional pictures being obtained. In 17% of the cases the hepatic process persited unmodified and in 10% ACH evolved towards cirrhosis.
- Published
- 2015