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In December 2019, the COVID-19 epidemic broke out in Wuhan (China), which soon spread worldwide, generating a pandemic that put the medical world in difficulty. In the absence of an etiological treatment and an effective vaccine, the researchers also turned their attention to alternative treatments, a series of plant molecules being analyzed by computer simulations regarding the inhibitory potential on the main proteins of SARS-CoV-2. A number of clinical trials based on traditional herbal formulas have also been initiated, especially by countries with a focus on alternative medicine. [ABSTRACT FROM AUTHOR]

The first cases of the new coronavirus SARS-CoV-2 were reported for the first time in people in Wuhan, China in December last year. The infection with the SARS-CoV-2 virus spread quickly in China, followed by outspread in other countries. It was declared a pandemic in March 2020. SARS-CoV-2 causes the disease COVID-19, an acute severe respiratory syndrome. Infections were reported in children of all ages, from newborn to adolescence, with a smaller incidence than in adults, and having a better prognostic than in adults. A particular evolutionary feature of the SARS-CoV-2 infection in children is Paediatric Inflammatory Multisystem Syndrome (PIMS), a rare but severe disease which is associated with COVID-19 and which has been reported to have been diagnosed in children from Europe and North America. Paediatric Inflammatory Multisystem Syndrome has similar characteristics to those of the Kawasaki disease and concomitant infection of SARS-CoV-2. A small percentage of children who have been diagnosed with severe acute respiratory syndrome determined by SARS-CoV-2 require hospitalisation and very few require care in the intensive care unit. The prevention of COVID-19 focuses on hand hygiene, wearing face masks in enclosed spaces and social distancing. [ABSTRACT FROM AUTHOR]

COVID-19 has been a continuing challenge for the entire medical world since SARS-CoV-2 spread rapidly around the globe from the Wuhan region of China. One of the multiple reasons for concern was the one related to the pregnant woman, the influence on the pregnancy, the fetal transmission, the possible teratogenic effects, the evolution of the newborn from the infected mother, the presence of the virus in breast milk. The data from the literature are still controversial, being necessary larger study because the final conclusions are still far from over. [ABSTRACT FROM AUTHOR]