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Thrombophilia is a disorder associated with an increased tendency to thrombosis. Thrombophilia can be acquired or hereditary. Only a few of the inherited thrombophilia present a major risk of thrombosis and they should be diagnosed when thromboembolic disease or miscarriages occur in pregnant women. It is important to know the personal history and the family history of the patients, to look for the cause of venous or arterial thromboembolism and to investigate the patients at risk in order to apply the prophylaxis and the anticoagulant treatment when necessary. A special attention should be given to patients with antiphospholipid syndrome, sometimes requiring anticoagulation indefinitely. [ABSTRACT FROM AUTHOR]

Arterial thromboembolism (ATE) is defined as an obstruction, usually followed by infarction of arterial beds. Aortic thromboembolism is clinically expressed by hind limb paresis or paralysis, the absence of reflexes, firm pelvic muscularity and hypersensitivity to manipulation, the impossibility of perceiving the femoral pulse, cold and cyanotic limbs. The therapeutic objectives in arterial thromboembolism therapy aim at managing pain, improving circulation and preventing the formation of new thrombi. [ABSTRACT FROM AUTHOR]

The postparum period is the highest risk period for thrombosis. The risk can be further stratified by maternal age and time since delivery. Risk of trombotic events persist until at least 12 weeks after delivery. Tromboembolic disease is the leading cause of maternal mortality in many countries. Starting from this fact, identification of those pregnant or post-partum women at high risk for thrombolism is especially important. This measure is necesary because those women need prophylaxis immediately in order to minimize the consequences of the disease. Another important issue that matters in the struggle with thrombosis is the knowledge of risk factors that lead to disease. One of the main benefits is to avoid some complications and to initiate from the begining an appropriate treatment. Doing that, the chances of recovery increase significantly. [ABSTRACT FROM AUTHOR]

The prevention of Venous Thromboembolism (VTE) in case of elderly patients with proximal femoral fracture benefits from a more and more complex range of anticoagulants which reduce the risk of pulmonary thromboembolism, a severe complication involving life-threatening risks. [ABSTRACT FROM AUTHOR]