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Copyright of Romanian Journal of Family Medicine / Revista Română de Medicina Familiei is the property of Media DOM Express and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Hepatitis C is a significant public health problem worldwide due to late-stage detection, when complications arise, because many cases of the disease are oligosymptomatic. Administration of direct antiviral treatment at the early stage of the disease leads to the eradication of the infection but involves many adverse effects that lead to waivers on the part of beneficiaries although the high costs are covered by national programs. Objective: To identify the risk factors involved in HCV transmission and to evaluate adverse reactions to antiviral administration, reason for discontinuing therapy that contributes to complications and increased HCV transmission. Method: Knowing the many adverse effects produced by the administration of direct antivirals, within the Faculty of Medicine in Brasov a prospective quantitative observational-transversal study was conducted between April and June 2021 having as data collection method the questionnaire addressed to patients diagnosed with hepatitis C distributed with the help of the non-governmental Organization Association of patients with liver disease in Romania and which included a number of 125 respondents-patients. Results: The study looked at the identification and frequency of risk factors that cause HCV contamination. Unfortunately, there is no vaccine to prevent hepatitis C infection, and the key to the problem is prevention and testing. The result of taking direct antivirals in addition to the undeniable benefits also brings adverse effects and their frequency is a reason for discontinuation of treatment for a fairly small percentage of patients, as evidenced by the present study, late initiation or its interruption leading to complications. Conclusion: The study found that the main risk factor identified by the respondents is dental treatment, more than half of the study participants had undetectable viremia from direct antiviral therapy, and nearly half of the 125 patients claimed that it had no adverse effect, in which case the benefits outweigh the risks. [ABSTRACT FROM AUTHOR]

The evolution of temporal lobe epilepsy often implies complex psychiatric manifestations, as the elements can be part of an aura, as well as of a psychiatric pathology of its own. This paper presents the case of a patient diagnosed with focal epilepsy of the right mesial temporal lobe, who subsequently developed psychotic disorder due to a general medical condition with medicolegal implications, treatment noncompliance and difficulties in controlling epileptic seizures. [ABSTRACT FROM AUTHOR]

It is a well known fact that tuberculosis treatment is long-term and difficult to be followed through. Nonadherence to treatment is associated with relapse and Mycobacterium strains resistance. The topic of this study was chosen due to the fact that Romania is an endemic country for tuberculosis, thus measures must be applied to decrease the incidence and the prevalence of this disease. Tuberculosis is a disease that should be treated seriously because of its high morbidity and mortality rates (WHO approximates that TB is one of the top 10 causes of death worldwide). The purpose of this study was to evaluate the patients' compliance towards the treatment in Harghita county. [ABSTRACT FROM AUTHOR]