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The authors discuss a possibility to estimate risk of chronic intoxication by 2,4-D agricultural preparations and phosphorus organic pesticides among rural inhabitants having occupational contact with the chemicals. The estimation could be based on lipid metabolism parameters.

The article represents materials describing examination of 540 workers engaged into mass poultry farming and characterizing the risk factors of neurovascular disorders. The authors identified the disorders' peculiarities of prevalence and pathogenetic mechanisms associated with lipid peroxidation and activity of antioxidant defence system.

The main unfavourable factor of poultry farms environment is contact of workers with chemical disinfectants. Changes in morphofunctional, cytochemical, immunological parameters and higher level of morbidity were revealed in poultry farms. Hygienic prophylactic recommendations were made.

The providing of hothouse workers with vitamins B1, B2, B6, PP, C and E was comprehensively evaluated basing on the study of their actual nutrition and biochemical parameters of their vitamin status--daily excretion of vitamins and their metabolites with urine, vitamin concentration in the blood serum and activity of erythrocytic vitamin-dependent enzymes with calculation of their activation coefficients. Multiple hypovitaminosis detected in the vegetable growers working in hothouses who received normal amounts of these essential nutrients with food, as well as the relationship noted between the vitamin-providing level and the length of working in the hothouse, evidence a possible influence of the occupational factors--the character of work attended by the action of toxic chemical compounds under conditions of the hothouse microclimate. Further investigations should be conducted to determine the vitamin requirements of hothouse workers.