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1. [Glutamate oxalacetate and glutamate pyruvate aminotransferase activity in Streptomyces hygroscopicus 155 producing antibiotic complex].

Author

Chipeva VA, Ivanova IV, and Gocheva B

Subjects
Alanine metabolism, Amino Acids metabolism, Ammonium Chloride chemistry, Anti-Bacterial Agents isolation & purification, Bacillus subtilis drug effects, Culture Media, Fermentation, Glycine metabolism, Microbial Sensitivity Tests, Streptomyces chemistry, Alanine Transaminase metabolism, Anti-Bacterial Agents pharmacology, Aspartate Aminotransferases metabolism, Streptomyces enzymology
Abstract

Antibiotic activity, aminotransferase activity and composition of intracellular amino acids in low and high potent variants of Streptomyces hygroscopicus 155 were studied. The data of the study are indicative of some general regularities characteristic of amino acid metabolism in actinomycetes: an increased pool of the main aminodonor amino acids (alanine, asparaginic and glutaminic acids) and an increased activity of aminotransferases in the cultures of both the variants when grown in media with readily assimilable nitrogen sources.

Published
1997

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