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Your search keyword '"Dopa Decarboxylase metabolism"' showing total 12 results
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12 results on '"Dopa Decarboxylase metabolism"'

1. [Tyrosine hydroxylase and dopa decarboxylase expression in the neurons of a mediobasal hypothalamic transplant].

Author

Fetisov SO

Subjects
Animals, Female, Hypothalamus, Middle embryology, Immunohistochemistry, Rats, Rats, Wistar, Brain Tissue Transplantation physiology, Dopa Decarboxylase metabolism, Fetal Tissue Transplantation physiology, Hypothalamus, Middle enzymology, Hypothalamus, Middle transplantation, Neurons enzymology, Tyrosine 3-Monooxygenase metabolism
Abstract

Specific antibodies were used for studying the expression of tyrosine hydroxylase (TH) and DOPA decarboxylase (DDC) in neurons of rat embryonic mediobasal hypothalamus (MBH), whose fragments were implanted into the third brain ventricle of the adult female Wistar rats. Two months after surgery, most immunopositive neurons expressed TH, smaller number of neurons expressed both TH and DDC, and few cells contained only DDC. As during development in situ, immunopositive neurons formed nuclei-like clusters located in the ventral region of the graft. This data suggest that MBH grafts contain a population of dopaminergic neurons and a population of TH-containing neurons that probably are not dopaminergic.

Published
1994

2. [Effect of euphylline and halidor on several indices of catecholamine and serotonin metabolism in the brains and blood of rats].

Author

Saratikov AS, Fisanova LL, and Marina TF

Subjects
Animals, Aromatic Amino Acid Decarboxylase Inhibitors, Brain enzymology, Catechol O-Methyltransferase metabolism, Catechol O-Methyltransferase Inhibitors, Dihydroxyphenylalanine metabolism, Dopa Decarboxylase metabolism, Dopamine metabolism, Epinephrine metabolism, Female, Male, Mice, Monoamine Oxidase metabolism, Norepinephrine metabolism, Rats, Aminophylline pharmacology, Bencyclane pharmacology, Brain metabolism, Catecholamines metabolism, Cycloheptanes pharmacology, Serotonin metabolism, Vasodilator Agents pharmacology
Abstract

Euphylline and galidore did not alter the concentration of catecholamines and serotonin in brain of intact rats, but exhibited opposite effects on metabolism of biogenic amines, if their precursors were administered into animals. Galidore decreased the activity of catechol-O-methyl transferase (COMT) and 5-hydroxytryptophane decarboxylase. Euphylline did not influence the COMT activity but increased the activity of 5-HT-decarboxylase. Both preparations did not alter the monoaminooxidase activity.

Published
1977

3. [Serotonin metabolism in acute renal ischemia].

Author

Ermolaev MV and Khovanskaia TP

Subjects
Acute Disease, Animals, Dopa Decarboxylase metabolism, Hydroxyindoleacetic Acid urine, Kidney blood supply, Ligation, Monoamine Oxidase metabolism, Rabbits, Renal Artery, Time Factors, Ischemia metabolism, Liver metabolism, Serotonin metabolism
Published
1975

4. [Possible mechanisms for the increase in serotonin content in amnesia caused by electroconvulsive shock].

Author

Getsova VM and Trofimov SS

Subjects
Animals, Blood-Brain Barrier drug effects, Brain metabolism, Cell Membrane Permeability drug effects, Conditioning, Classical, Dopa Decarboxylase metabolism, Enzyme Repression, Fluoresceins pharmacology, Humans, Injections, Intraperitoneal, Male, Rats, Serotonin pharmacology, Spectrometry, Fluorescence, Time Factors, Amnesia metabolism, Electroshock, Serotonin metabolism
Published
1975

5. [Cerebral catecholamines in experimental excessive emotional stress].

Author

Belova TI and Kvetnanskiĭ R

Subjects
Animals, Blood Pressure, Dopa Decarboxylase metabolism, Dopamine metabolism, Dopamine beta-Hydroxylase metabolism, Epinephrine metabolism, Humans, Hypertension metabolism, Locus Coeruleus metabolism, Norepinephrine metabolism, Phenylethanolamine N-Methyltransferase metabolism, Rats, Restraint, Physical adverse effects, Tyrosine 3-Monooxygenase metabolism, Brain metabolism, Catecholamines metabolism, Stress, Psychological metabolism
Published
1981

6. [Serotonin metabolism in the duodenal tissue of intact rabbits].

Author

Ermolaev MV and Semenova MV

Subjects
Animals, Dopa Decarboxylase metabolism, Hydroxyindoleacetic Acid metabolism, Monoamine Oxidase metabolism, Rabbits, Duodenum metabolism, Serotonin metabolism
Abstract

Serotonin, 5-oxyindolacetic acid content, and monoaminooxidase activity proved to exceed such in the kidney of rabbit. This pointed to the high capacity of the intestine in respect to the accumulation of serotonin and the processes of its catabolism. The reverse regularity was noted for 5-oxytryptophanedecarboxylase, the activity of which was about 12 times greater in the kidney than in the intestine, this apparently characterizing a low capacity of this tissue in the course of decarboxylation of 5-oxytryptophane.

Published
1978

7. [Serotonin metabolism in acute renal ischemia in rabbits].

Author

Ermolaev MV and Khovanskaia TP

Subjects
Acute Disease, Animals, Clinical Enzyme Tests, Dopa Decarboxylase metabolism, Enzyme Activation, Enzyme Repression, Kidney enzymology, Ligation, Monoamine Oxidase metabolism, Rabbits, Renal Artery, Time Factors, Ischemia metabolism, Kidney blood supply, Serotonin metabolism
Abstract

In tissue of ischemic kidney of rabbits a 5-hydroxytryptophan decarboxylase activity was decreased at first 15 min of ischemia; in contralateral kidney it was slightly increased. Then, within all the studied periods (24 hrs), activity of the enzyme was gradually decreased in both kidneys. The monoamine oxidase activity (substrates serotonin and p-nitrophenyl ethylamine) changed alternatively in early periods of ischemia; it tended to increase, especially in contralateral kidney, within 3 hrs after constriction of kidney artery.

Published
1975

8. Serotonin metabolism in duodenal tissue in acute renal ischemia in rabbits.

Author

Ermolaev MV and Semenova MV

Subjects
Acute Disease, Animals, Dopa Decarboxylase metabolism, Enzyme Activation, Hydroxyindoleacetic Acid metabolism, Monoamine Oxidase metabolism, Rabbits, Duodenum metabolism, Ischemia metabolism, Kidney blood supply, Serotonin metabolism
Abstract

Metabolism of serotonin was studied in duodenum of rabbits in acute kidney ischemia (from 15 min to 1 hr). Estimations of serotonin and 5-hydroxy indolacetic acid content and the activities of 5-hydroxytryptophane decarboxylase (5-HTD) and monoamine oxidase (MAO) using serotonin as a substrate were carried out. A complicated phase dynamics in the intestine of main patterns of serotonin metabolism was observed in acute kidney ischemia. Within the ischemic period content of serotonin and the MAO activity correlated with the activity of 5-HTD in the duodenal tissue. The alterations in the activity of MAO from intestine suggest that this enzyme was especially important in the serotonin metabolic conversions studied.

Published
1977

9. [Structure and function of chromaffin cells].

Author

Blashko G

Subjects
Adenosine Triphosphate metabolism, Adrenal Medulla enzymology, Animals, Catecholamines biosynthesis, Dopa Decarboxylase metabolism, Lysophosphatidylcholines metabolism, Methyldopa metabolism, Organoids, Proteins metabolism, Tissue Extracts, Ultracentrifugation, Adrenal Medulla cytology, Catecholamines metabolism, Chromaffin System cytology, Chromaffin System enzymology, Chromaffin System metabolism
Published
1967

10. [Effect of antitumor preparations on the enzymes of serotonin metabolism in the liver of mice].

Author

Baumanis EA, Elksnite IE, and Liepinia VA

Subjects
5-Hydroxytryptophan metabolism, Animals, Cyclophosphamide pharmacology, Dopa Decarboxylase metabolism, Enterovirus, Fluorouracil pharmacology, Liver drug effects, Male, Mice, Monoamine Oxidase metabolism, Serotonin biosynthesis, Streptonigrin pharmacology, Thiotepa pharmacology, Zymosan pharmacology, Antineoplastic Agents pharmacology, Liver enzymology, Serotonin metabolism
Published
1973

11. [5-hydroxytryptophan decarboxylase activity in benign tumors in man].

Author

Popova GN, Berezov TT, and Burobina SS

Subjects
5-Hydroxytryptophan metabolism, Humans, In Vitro Techniques, Reserpine pharmacology, Serotonin biosynthesis, Time Factors, Tryptophan metabolism, p-Methoxy-N-methylphenethylamine pharmacology, Dopa Decarboxylase metabolism, Nasal Polyps enzymology
Published
1973

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