1. [Effectiveness and the methods of using streptokinase in myocardial infarct and preinfarct stenocardia].
- Author
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Liusov VA, Koniaev BV, Belousov IuB, Iakovlev VB, Keller H, Wegner H, and Sheel H
- Subjects
- Angina Pectoris complications, Anticoagulants therapeutic use, Drug Evaluation, Electrocardiography, Humans, Myocardial Infarction complications, Shock, Cardiogenic drug therapy, Time Factors, Angina Pectoris drug therapy, Myocardial Infarction drug therapy, Streptokinase administration & dosage
- Abstract
The effectiveness of streptokinase treatment of patients with myocardial infarction as compared to the control group and patients given anticoagulants is analysed. It is shown that the frequency of recurrent myocardial infarctions, congestive circulatory insufficiency, shock, and thromboembolic complications is lower in the group of patients treated with streptokinase than in the control group. Streptokinase improves the course of the disease and the prognosis in patients with preinfarction angina pectoris. The effect of streptokinase is higher in the first 3--6 hours after the development of myocardial infarction and in individuals under the age of 65. The effectiveness of the treatment does not diminish when the drug is injected for a short time and in small doses (300,000--750,000 U).
- Published
- 1980