1. Hand osteoarthritis: pathogenesis, diagnosis, and approaches to therapy
- Author
-
N. A. Shostak, N. G. Pravdyuk, A. M. Lila, and O. A. Gromova
- Subjects
medicine.medical_specialty ,chondroguard ,Functional failure ,Immunology ,Disease ,Osteoarthritis ,capsaicin ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Internal medicine ,Immunology and Allergy ,Medicine ,Pharmacology (medical) ,In patient ,030212 general & internal medicine ,Pathological ,chondroitin sulfate ,estrogen-containing drugs ,030203 arthritis & rheumatology ,nonsteroidal anti-inflammatory drugs ,hand osteoarthritis ,glucosamine sulfate ,business.industry ,Widespread Disease ,vitamin d ,medicine.disease ,targeted therapy ,Hand joint ,Joint damage ,sustaguard arthro ,business - Abstract
Osteoarthritis (OA) is a widespread disease accompanied by persistent joint damage with obvious functional failure, which leads to early disability in patients. In OA, different groups of joints are involved in the pathological process. Hand joints are one of the classical sites of OA. The paper discusses the role of mechanical load, genetic factors, and sex hormone deficiency in the development of the disease. The treatment policy includes a set of non-pharmacological, pharmacological, and surgical methods.
- Published
- 2019