1. [Late-onset rheumatoid arthritis in a patient with successfully treated IgA nephropathy].
- Author
-
Chebotareva NV, Bobkova IN, and Gulyaev SV
- Subjects
- Adult, Antihypertensive Agents administration & dosage, Antirheumatic Agents administration & dosage, Disease Management, Disease Progression, Humans, Kidney Function Tests methods, Leflunomide, Male, Patient Acuity, Treatment Outcome, Arthritis, Rheumatoid complications, Arthritis, Rheumatoid diagnosis, Arthritis, Rheumatoid drug therapy, Arthritis, Rheumatoid physiopathology, Enalapril administration & dosage, Glomerulonephritis, IGA diagnosis, Glomerulonephritis, IGA drug therapy, Glomerulonephritis, IGA etiology, Glomerulonephritis, IGA physiopathology, Isoxazoles administration & dosage, Kidney pathology
- Abstract
The paper describes a rare clinical case of rheumatoid arthritis (RA) that developed in a patient 9 years after diagnosing IgA nephropathy. Kidney disease was characterized by a stable course with moderate urinary syndrome, hypertension, and reduced renal function. Immunosuppressive therapy using glucocorticosteroids and then mycophenolic acid led to remission of nephritis and recovery of renal function. However, the absence of nephritis activity and discontinuation of immunosuppressants was responsible for articular syndrome. The diagnosis of RA is based on its characteristic radiological patterns and immunological characteristics after ruling out a number of systemic diseases and infections. The common pathogenetic components of IgA nephropathy and RA, including the role of rheumatoid factor IgA, are discussed.
- Published
- 2017
- Full Text
- View/download PDF