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Modern investigations in biology often require the efforts of one or more groups of researchers. Often these are groups of specialists from various scientific fields who generate and share data of different formats and sizes. Without modern approaches to work automation and data versioning (where data from different collaborators are stored at different points in time), teamwork quickly devolves into unmanageable confusion. In this review, we present a number of information systems designed to solve these problems. Their application to the organization of scientific activity helps to manage the flow of actions and data, allowing all participants to work with relevant information and solving the issue of reproducibility of both experimental and computational results. The article describes methods for organizing data flows within a team, principles for organizing metadata and ontologies. The information systems Trello, Git, Redmine, SEEK, OpenBIS and Galaxy are considered. Their functionality and scope of use are described. Before using any tools, it is important to understand the purpose of implementation, to define the set of tasks they should solve, and, based on this, to formulate requirements and finally to monitor the application of recommendations in the field. The tasks of creating a framework of ontologies, metadata, data warehousing schemas and software systems are key for a team that has decided to undertake work to automate data circulation. It is not always possible to implement such systems in their entirety, but one should still strive to do so through a step­by­step introduction of principles for organizing data and tasks with the mastery of individual software tools. It is worth noting that Trello, Git, and Redmine are easier to use, customize, and support for small research groups. At the same time, SEEK, OpenBIS, and Galaxy are more specific and their use is advisable if the capabilities of simple systems are no longer sufficient.

Center of Pharmaceutical Analytics purchased and installed LabWare LIMS laboratory information system, LabWare ELN electronic laboratory journals from LabWare company. At the moment, the system is integrating into the work of the laboratory, templates for research work are created and employees are trained. The article opens a series of articles of the integration of the LIMS system into the work of the analytical center. LabWare has received universal recognition, is a leader in the global market of global Laboratory information systems (LIMS) and has a wide range of loyal users.

This article describes the results of Laboratory Information Management System implementation in an expert institution dealing with medicines evaluation. The purpose of the study was to evaluate the feasibility of providing digital support to the laboratories of the Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» of the Ministry of Health of the Russian Federation and to assess the functionality of the information system in terms of coverage of functional capabilities of various classes of laboratory software. The implementation of laboratory automation systems is required by the current regulations and is in line with international approaches to organisation of the quality management. The information system implementation made it possible to computerize management of drug samples, distribution of assignments among responsible employees, storage and management of documents, and reporting of test results. It created opportunities for direct integration with laboratory equipment allowing for creation of analytical protocols without manual data transfer. The implemented solution meets all requirements and standards for the functional capabilities of laboratory information systems. A similar system could be used in chemical, pharmacological, medical and biochemical laboratories, its implementation will make it possible to meet both national and international standards. These innovations are part of the concept of CALS/PLM technologies integration into institutions management programmes.