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The article provides an overview of the history of the development of Russian language teaching in the PRC, highlighting the main stages and their features. It is noted that teaching the Russian language in the PRC has always been associated with the national strategy for training personnel for the socio-economic development of the country, that is, setting educational goals and developing curricula are always carried out taking into account the immediate future and long-term plans for the modernization of the country. Analysis of the changes that took place in the field of Russian-language education in China at different stages made it possible to rethink and generalize the accumulated positive experience and at the same time highlight the shortcomings and bottlenecks in the process of organizing the teaching of the Russian language, outline steps to overcome them and improve the Russian-language education system as a whole. Using the example of Harbin Polytechnic University (HPU), the main characteristics of a comprehensive model for teaching the Russian language to students of engineering and technical specialties have been identified.

The theory of academic exchanges emphasises the importance of international cooperation to improve the quality of education, stimulate innovation and promote cultural diversity. China and Russia are two major world powers with rich history and culture. The exchange of international students between the countries is an important aspect of the friendly format of cooperation in higher education. During such exchange, students can improve their foreign language skills, enrich their personal life experience, ensure high competitiveness in employment, and expand their knowledge and skills in the field of their profession. This paper analyses the current situation and predicts future directions of educational exchange through various prisms, including the experience of academic student exchange between universities in the two countries. It analyses the attitudes of Chinese students studying at SPbSU towards higher education in Russia. The author notes that academic exchanges and foreign learning experiences provide opportunities for international students to broaden their horizons and fulfil their emotional needs in study and life. Students from both countries have the opportunity to immerse themselves in a different cultural and academic environment, improve their intercultural communication skills and broaden their global perspectives. It also focuses on the opinion of Chinese students about the quality of higher education in Russia. Academic exchanges of students are of great importance for the state, as they act as instruments of forming «soft power» in another country, strengthen diplomatic relations between countries, form a positive image of the state, attract investments, etc. Thus, academic exchanges are a way for countries to develop cooperation at various levels - from educational to economic. Thus, academic exchanges are a way for countries to develop co-operation at various levels - from educational to economic. Purpose. To investigate the current state of the concept of academic student exchange between China and Russia, to study the significance of this international co-operation for the development of the higher education system. Methodology. The paper uses collection and analysis of information sources, historical method, comparison and generalisation, survey with the help of the author's questionnaire. SPSS Statistics 23 software is used to analyse empirical data. Results. The result of the work is the identification of the peculiarities of the sphere of academic exchange of students between China and Russia, the determination of the importance of this cooperation for the development of the higher education system at the international level. The author concludes that cooperation in the development of innovations in key areas of education contributes to the smoothing of cultural differences between the countries, and expands opportunities for students of both countries in higher education. Practical implications. The results of the study can be used in the educational sphere of international cooperation. Teachers and specialists involved in planning the educational process in the university sphere have the opportunity to create an innovative approach to improve the academic exchange programme for students, taking into account the socio-cultural criteria analysed in the article.

This article proposes an approach for designing a general subsystem of automatic generation of questions in intelligent learning systems. The designed subsystem allows various types of questions to be automatically generated based on information from the knowledge bases and save the generated questions in the subsystem knowledge base for future use. The main part of the subsystem is the automatic generation module of questions, which allows one to generate questions of various types based on existing question generation strategies in combination with the structural characteristics of knowledge bases built using OSTIS technology. In this article, a variety of strategies for automatically generated questions are proposed, the use of which allows various types of questions to be automatically generated, such as multiple-choice questions, fill-in-the-blank questions, questions of definition interpretation and etc. The most important part of the subsystem is the knowledge base, which stores the ontology of questions, including the question instances themselves. In this article, the knowledge base is constructed based on OSTIS technical standards. The type classification of automatically generated questions was developed, as well as the subject area for storing generated questions and the corresponding ontology described in the knowledge base of the subsystem. The generated questions are stored in the subsystem knowledge base in the form of SC-code, which is the OSTIS technology standard. When testing users, these automatically generated questions are converted to the corresponding natural language form through the natural language interface. Compared with the existing approaches, the approach proposed in this article has certain advantages, and the subsystem designed using this approach can be used in various OSTISbased systems driven by OSTIS technology.

Contemporary linguistics, especially the research achievements of contrastive linguistics and text linguistics injected creative vigor into translation, which brought about the field of contrastive text. In view of the above, we adopt a new objective research method of systemic functional linguistics to analyze the Russian version of the poem Qingming. This study is based on Halliday's theory of metafunctions of language.

The results of the survey of students in Guangzhou which ranks third among major cities in China in terms of social, economic and demographic indicators are presented in the article. The aim of the research was not only to reveal Chinese youth priorities in the sphere of education, private life, work, social activity and morality, but also to provide characteristics of value system of the students of the major regional centre versus the corresponding answers of the respondents in Beijing. The comparative analysis of the value system of students in metropolitan and regional institutions of higher education was carried out in the framework of the following theme-based modules: the total level of political and social involvement and activity, the choice of achievement criteria, educational and professional strategies, family and marriage relations, etc.

In this study, we explored the effects of treating human endometrial cancer cells with γ-synuclein-specific short hairpin RNA (shRNA) and elucidated the associated mechanisms in vitro and in vivo through the p38, extracellular signal-regulated kinase (ERK), and c-Jun N-terminal kinase (JNK) signaling pathways. Cell proliferation and migration were assessed using CCK8, Transwell, and scratch wound healing assays. Flow cytometry and laser scanning confocal microscopy were used to detect cell cycle changes. Relative levels of phosphorylated and non-phosphorylated (p) p38, ERK1/2 and JNK1/2/3 were determined in vitro and in vivo using simple western blotting assays. Cell proliferation in the experimental group decreased significantly and cells transfected with shRNA showed reduced migration rates (P < 0.05). p-p38, p-ERK1/2, and p-JNK1/2/3 levels were downregulated in the experimental group in vitro and in vivo. Tumor volumes and weights in the experimental group were significantly lower (P < 0.05). Tumor formation time in the negative control group was significantly shorter (P < 0.05). Flow cytometry showed that the number of cells in the G1 and mitotic phases increased and that in the S phase decreased after SNCG silencing (P < 0.05). Confocal microscopy showed that the percentage of cells in the mitotic phase increased after SNCG gene silencing (P < 0.05). We conclude that shRNA-mediated suppression of γ-synuclein decreased the proliferation, migration, and tumorigenicity of endometrial cancer cells via downregulation of p38, ERK, and JNK phosphorylation. High SNCG expression is closely related to the growth cycle of endometrial cancer cells.

Sumac is universally known for its abundance of raw lacquer. Toxicodendron vernicifluum (Stokes) F.A. Barkley is one of the widely distributed native sumac cultivars. To accelerate sumac breeding for more prolific, high-quality, and robust cultivars, it is essential to explore its lacquer metabolism. However, transcriptomic and genomic data available for sumac are still limited. In this study, we generated the transcriptomic profiles of triploid Toxicodendron vernicifluum CV. Dahongpao (Dahongpao) and diploid T. vernicifluum and Toxicodendron vernicifluum CV. Huoyanzi (Huoyanzi), with 87856 unigenes. About 53% of these unigenes were annotated using Nr, Swiss-Prot, Kyoto Encyclopedia of Genes and Genomes (KEGG), Cluster of Orthologous Groups (COG) and Gene Ontology (GO). We identified nine differentially expressed candidate genes associated with type III polyketide synthase formation, which is the first step in urushiol biosynthesis. Additionally, a number of simple sequence repeats (EST-SSRs) were identified in T. vernicifluum for further molecular marker-assisted breeding. This study is the first report of Toxicodendron species transcriptome.

The outmost layer of the surface of any land plant is covered with wax, which protects the inner tissues of plants. The Arabidopsis ATP binding cassette (ABC) transporter, Cer5, was found to be an exporter of wax molecules. Full-length wheat tacer5 cDNA, a sequence homologous to cer5, was isolated. Similar to other transporters of the ABCG subfamily, TaCer5 also has a typical basic structure of NBD-MSD (nucleotide-binding folds domain - membrane-spanning domain). Although the identity scores of TaCer5 and other ABCG transporters are not very high, amino acid residues of NBDs and MSDs are highly conserved among them. Tacer5 is a tissue-specific gene. The transcripts of tacer5 were found in leaf tissues and predominantly in stem tissues but were hardly detectable in root tissues. Stress inhibited the expression of tacer5. The expression was significantly decreased by salinity, low temperature, and 48-hour-darkness and also by exogenous phytohormone abscisic acid and salicylic acid, although not significantly. Exposure to polyethylene glycol either increased the expression or decreased it, depending on the duration of exposure. All the above factors also decreased the extent of wax deposited on wheat leaves. It is therefore concluded that transport of wax molecules is affected by environmental factors.

The information on the carbohydrate specificity and molecular organization of some carbohydrate-binding proteins (lectins) of marine invertebrates is reported. Antiviral activity of some of the lectins against human immunodeficiency virus has been studied. Lectins of marine invertebrates are promising tools for studying natural glycoconjugates and cell effectors in vitro.