Search

Your search keyword '"Myocardial Reperfusion Injury genetics"' showing total 2 results
Start Over Descriptor "Myocardial Reperfusion Injury genetics" Language russian
2 results on '"Myocardial Reperfusion Injury genetics"'

1. [Ischemia-Reperfusion Injury: Molecular Mechanisms of Pathogenesis and Methods of Their Correction].

Author

Goncharov RG and Sharapov MG

Subjects
Humans, Signal Transduction, Oxidative Stress, Myocardial Reperfusion Injury genetics, Reperfusion Injury genetics, Reperfusion Injury pathology, Myocardial Infarction
Abstract

Ischemia-reperfusion is a cascade of complex and interrelated pathological processes underlying many human diseases, including such socially significant diseases as stroke, myocardial infarction, acute renal failure, etc. The present review considers modern ideas about the main biochemical and signal-regulatory processes in the cell under conditions of ischemia-reperfusion. Both generally accepted and newly developed ways of ischemia-reperfusion lesion correction aimed at different chains of this pathological process are considered.

Published
2023
Full Text
View/download PDF

2. [TRIGGER, SIGNALING MECHANISM AND END EFFECTOR OF CARDIOPROTECTIVE EFFECT OF REMOTE POSTCONDITIONING OF HEART].

Author

Maslov LN, Mukhomedzvanov AV, and Sementsov AS

Subjects
Adenosine metabolism, Aldehyde Dehydrogenase genetics, Aldehyde Dehydrogenase metabolism, Animals, Gene Expression Regulation, Humans, Large-Conductance Calcium-Activated Potassium Channel alpha Subunits genetics, Large-Conductance Calcium-Activated Potassium Channel alpha Subunits metabolism, Myocardial Reperfusion Injury genetics, Myocardial Reperfusion Injury pathology, Myocardium pathology, Peptides genetics, Phosphatidylinositol 3-Kinases genetics, Phosphatidylinositol 3-Kinases metabolism, Protein Kinase C genetics, Protein Kinase C metabolism, Proto-Oncogene Proteins c-akt genetics, Proto-Oncogene Proteins c-akt metabolism, Ischemic Postconditioning, Myocardial Reperfusion Injury metabolism, Myocardium metabolism, Nitric Oxide metabolism, Peptides metabolism, Signal Transduction genetics
Abstract

Trigger of remote postconditioning (RP) is high molecular weight peptide(s). Nitric oxide and adenosine act as intermediaries between the peptide and the intracellular structures. The autonomic nervous system is not involved in the RP. In RP signaling mechanism protein kinase C, PI3 kinase, Akt kinase, aldehyde dehydrogenase are involved. A hypothetical end effector of RP is BKca channel.

Published
2015

Catalog

Books, media, physical & digital resources
See catalog results