1. [Monoamines and reproductive function of rats selected for strengthening of catatonia response].
- Author
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Klochkov DV, Alekhina TA, Kuznetsova EG, and Barykina NN
- Subjects
- Animals, Body Weight, Female, Hypothalamus metabolism, Organ Size, Ovary anatomy & histology, Rats, Rats, Wistar, Uterus anatomy & histology, Catatonia genetics, Dopamine metabolism, Estrous Cycle, Norepinephrine metabolism, Testosterone blood
- Abstract
Weights of the body, ovaries, and uterus; estrous cycles and the contents of dopamine (DA) and norepinephrine (NE) in the hypothalami, and testosterone in blood plasma of GC females were studied at various estrous stages (diestrus and estrus). The outbred Wistar line was used as a control. In addition to reduced body weight in GC females, we observed disturbed morphological cyclic linkages between the ovaries and uterus: ovary weight reduction in diestrus (p < 0.01) and lower estrogen-related increase in uterus weight in estrus in GC females in comparison with Wistar ones. While the contents of DA and NE in GC hypothalami were reduced, the levels of these monoamines were high in estrus and low in diestrus. Testosterone levels in GC female plasma in diestrus were higher than in estrus or in Wistar rats.
- Published
- 2008