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To define the range of histio- and organotypical capacities of rat soft palatine and bronchial epithelia, and to elucidate the nature of the effect of neuroendocrine factors of hypothalamic paraventricular factors upon them, the experiments were conducted by co-culturing mucosal fragments of oral and pharyngeal surfaces of soft palate and bronchi with the paraventricular nuclei-containing hypothalamic fragments using in vivo F.M. Lazarenko method. Soft palatine and bronchial epithelia were found to have similar histoblastic properties. The stimulating effect of hypothalamic factors, released paraventricular nuclei, on the processes of regeneration of epithelia and of connective tissue was noted.

Processes of the development and growth of the soft palate mucosas in ontogenesis and also proliferation, growth and differentiation of epithelial structures were studied in the experiment. The epithelium of the soft palate nasal surface was established to be more labile and to be characterized with polymorphism forming single-layer and pseudostratified structures. Under these conditions the oral surface epithelium keeps stratified structures firmly. On the basis of discovered differences of the epithelium biological qualities a suggestion is made on the different genetic origin of epithelial tissues of mucosas of the soft palate oral and pharyngeal surfaces.