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Methods of synthesis of prostaglandin fluorides were developed and their properties were investigated. These compounds were shown to be convenient synthetic precursors for obtaining esters and amides of natural prostaglandins and their fluorodeoxy analogues.

The review of works of the authors devoted to the synthesis of low-molecular bioregulators with the use of unsaturated sugars is presented. The schemes of synthesis of insect pheromones and acetogenins and glycosphingolipids on the basis of glycals are discussed. The pathways of synthesis of triterpene 2-deoxy-alpha-glycosides are shown. The synthesis of prostanoids from levoglucosenone is considered.

Several novel prostaglandins containing an amide group in the alpha-chain have been prepared by the mixed carbonic anhydride method from 3 alpha-tetrahydrofuranyloxy-5-hydroxyimino-2 beta-(3 alpha- tetrahydrofuranyloxy-trans-1-octenyl)-cyclopentane-1 alpha-acetic acid and omega-amino acids with a linear chain of varying length (CH2-group number from 1 to 7). The physico-chemical properties of the title compounds were studied.

Synthesis of a number of model triglycerides and lysoglycerides bearing the acyl moieties of 11-deoxyprostaglandin E1, and palmitic acid residues has been carried out.