1. [Reproduction of leukovirus RD-114 in diploid and heteroploid human cells].
- Author
-
Sevast'ianova MV, Zakharova LG, Gerasina SF, Sushko NI, and Al'tshteĭn AD
- Subjects
- Animals, Cell Line, Chromosome Aberrations, Diploidy, Hemangiosarcoma, Humans, Kidney, Lung embryology, Mice embryology, RNA-Directed DNA Polymerase metabolism, Rats embryology, Retroviridae enzymology, Rhabdomyosarcoma microbiology, Retroviridae growth & development, Virus Replication
- Abstract
The capacity of leukovirus RD-114 to replicate in human embryo lung diploid cell cultures and continuous human angiosarcoma cell cultures (AS and 709 lines). Differences in the capacity to support the virus reproduction were observed in the two strains of human embryo lung cells (HEL-1 and HEL-3) and the two continuous angiosarcoma cell lines. No virus reporduction was observed in mouse and rat cell cultures. No cytopathic or transformation changes were caused by the virus in any of the systems examined.
- Published
- 1975