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Your search keyword '"Shloma DV"' showing total 8 results
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8 results on '"Shloma DV"'

1. [The role of suppressor cells in the mother-fetus system].

Author

Shloma DV, Terpiliak OI, and Sozanskiĭ OA

Subjects
Female, Fetus immunology, Humans, Immunity, Cellular immunology, Pregnancy, T-Lymphocytes immunology, Maternal-Fetal Exchange immunology, T-Lymphocytes, Regulatory immunology
Published
1991

2. [Natural killer cells in the interferon therapy of cancer patients].

Author

Shparyk IaV, Bilynskiĭ BT, and Shloma DV

Subjects
Antigens, CD immunology, Antigens, Neoplasm immunology, Humans, Immunity, Innate drug effects, Immunity, Innate immunology, Killer Cells, Natural drug effects, Neoplasms therapy, Interferons therapeutic use, Killer Cells, Natural immunology, Neoplasms immunology
Published
1991

3. [Genetic mechanisms for the regulation of natural killer cell activity].

Author

Shparyk IaV and Shloma DV

Subjects
Animals, Humans, Mutation, Killer Cells, Natural physiology, Major Histocompatibility Complex genetics
Abstract

The problems on genetic mechanisms of regulation of natural killer cells, participation of major histocompatibility complex in these processes are considered. The examples of mutations and hereditary diseases accompanied by disfunction of the natural killer activity are presented. It is supposed that genetic predisposition of natural killer activity depression can promote an increase in the risk of malignant and autoimmune diseases.

Published
1990

4. [Indices of the natural immunity system in patients with rectal cancer undergoing radiation treatment].

Author

Bilynskiĭ BT, Gnatyshak EA, Polishchuk IaE, Shloma DV, and Shparik IaV

Subjects
Cytotoxicity Tests, Immunologic, Female, Humans, Immune Tolerance radiation effects, Immunity, Innate radiation effects, Killer Cells, Natural immunology, Killer Cells, Natural radiation effects, Male, Middle Aged, Radioisotope Teletherapy, Rectal Neoplasms radiotherapy, Rectal Neoplasms immunology
Published
1988

6. [Sensitivity of a continuous cell culture of human ovarian carcinoma to interferon preparations of different origins].

Author

Timofeev IV, Krispin TI, and Shloma DV

Subjects
Animals, Antiviral Agents pharmacology, Cattle, Cells, Cultured, Chick Embryo, Drug Evaluation, Preclinical, Drug Resistance, Encephalomyocarditis virus drug effects, Female, Humans, Swine, Vesicular stomatitis Indiana virus drug effects, Interferons therapeutic use, Ovarian Neoplasms therapy
Abstract

A comparative study of homologous (human) and heterologous (porcine and bovine) leukocyte interferon preparations showed them to have antiviral and antiproliferative effects on CaOv tumor cells culture derived from human ovary carcinoma. These effects were lower in heterologous than in homologous interferon preparations.

Published
1982

7. [Effect of a number of antitumor preparations on RNA- and protein-synthesizing processes and viral interferon induction in Krebs 2 ascites carcinoma cells].

Author

Shloma DV, Krispin TI, and Balandin IG

Subjects
Animals, Carcinoma, Krebs 2 immunology, Carcinoma, Krebs 2 metabolism, Cell-Free System drug effects, Cells, Cultured, Drug Evaluation, Preclinical, Encephalomyocarditis virus immunology, In Vitro Techniques, L Cells immunology, L Cells metabolism, Mice, Newcastle disease virus immunology, Antineoplastic Agents therapeutic use, Carcinoma, Krebs 2 drug therapy, Interferons biosynthesis, Neoplasm Proteins biosynthesis, RNA, Neoplasm biosynthesis
Abstract

Antitumor drugs: adenosine cyclophosphane, adenosine thiophosphamide, colchamine thiophosphamide, and tribetamide inhibited RNA biosynthesis in Krebs-II ascitic carcinoma cells and in similar concentrations they were much less inhibiting for protein-synthesizing processes (in cells and cell-free protein-synthesizing system). The drugs could inhibit interferon synthesis, possibly after virus induction, in Krebs-II ascitic carcinoma cells only in concentrations significantly inhibiting the synthesis of cellular macromolecules.

Published
1982

8. [Effect of inhibitors that destroy cytoskeleton structures on the antiviral and antiproliferative activity of interferons].

Author

Solov'eva MF, Krispin TI, Shloma DV, Kalmakhelidze KA, and Balandin IG

Subjects
Animals, Cell Division drug effects, Cytopathogenic Effect, Viral drug effects, Drug Synergism, Encephalomyocarditis virus drug effects, Humans, L Cells, Mice, Tumor Cells, Cultured, Cytoskeleton drug effects, Interferons antagonists & inhibitors, Interferons pharmacology
Abstract

The effect of a number of drugs (vincristine, vinblastine, cytochalasin B, colcemid, colchamine) destroying cytoskeleton structures (microtubules and microfilaments) in combination with homologous interferon was studied in L920 and CaOv cells. The above substances were shown to inhibit the antiviral and enhance (from additivity to synergism) the antiproliferative effect of interferons under study.

Published
1988

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