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By weighting and mathematical analysis dynamics of relative weight of suprarenal glands, thymus and spleen of 2, 6 and 12 month male Wistar rats, exposed to repeated influence of gravitational overload (9 g) during 10 and 30 days were studied. Dependence of changes of relative weight of animal organs on age and multiplicity of systematic hypergravitation influence was exposed. It is determine that 2 and 6 month rats possess the most capabilities of adaptation to repeated gravitational overloads. 12 month rats, revealing relative resistance to ten-fold gravitational overload, at continuous repeating overloads (30 days), reveal the depletion regulatory systems of organism tendency.