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Start Over Descriptor "Tgr5" Language russian
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1. MEMBRANE BILE ACID RECEPTOR TGR5 - A NEW TARGET IN THE STUDY OF METABOLIC, INFLAMMATORY AND NEOPLASTIC DISEASES

Author

O. M. Drapkina and E. I. Fomicheva

Subjects
tgr5, bile acids, metabolic disorders, obesity, inflammation, carcinogenesis, Therapeutics. Pharmacology, RM1-950, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

TGR5 are G-protein-linked, membrane bile acids receptors that widely express in tissues of animals and humans. Namely tissue localization of TGR5 determines biological effects of activation of these receptors. This review focuses on the role of TGR5 as a new pharmacological target for the treatment of patients with metabolic syndrome, diabetes, obesity, atherosclerosis, liver disease and cancer processes.

Published
2016
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