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Recently collated scientific data on the management of C1 clinical class of chronic venous disorders; wide prevalence of the disease and high variability amongst medical practitioners in relation to managing this category of patients and absence of any regulatory documents has prompted the development of clinical guidelines for the treatment of patients with reticular varicose veins and telangiectasias of the lower extremities and various parts of the body. These guidelines have been developed by a self-regulated organization Association “The National College of Phlebology”. The purpose of the de novo guidelines is to systematize the existing evidence and offer minimal standards of care for chronic venous disorders in C1 patients.

As a rule there are significant changes in the capital structure due to mergers and takeovers that's why the management task at the prediction stage is a correct evaluation of these changes influence on the cost of the future company. This article contains methods of evaluating the capital structure influence on the company cost within different evaluation approaches and the most detailed description of the methods used within the income approach. Here is a method of calculating a weighted average cost of capital based on the capital asset pricing model (CAPM) and restrictions connected with this model use. It is defined whether there is a necessity to correct the predicted cost of attracting own or borrowed assets.