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Peculiarities of deformity of the left ventricle (LV) walls were studied in 93 patients in various variants of hypertrophic cardiomyopathy (HCMP). In accordance to complex echocardiography data, including vector-echocardiography, in HCMP the deformity grade and quantity of the affected segments of the LV myocardium have had depended directly on the stenosis degree of the LV tractus deferens (TD). Initially, a capacity for deformity lowers in basal segments of interventricular septum and in the LV anterior wall. While progressing of the LV TD obstruction, other myocardium segments become involved in the process, what is accompanied by deepening of the cardiac insufficiency (CI) severity. In maximal affection of myocardium and mostly expressed signs of CI gradient of systolic pressure in LV TD have had eliminated, in spite of presence of the LV expressed hypertrophy.

Examination of 32 patients with isolated systolic arterial hypertension (office blood pressure 171.9 = -3.3/79.7 +/- 0.2 mm Hg) and 54 ones with systolic/diastolic hypertension) 179.8 +/- 3.9/114.8 +/- 1.9 mm Hg) showed that the former are characterized by isolated hypertrophy of interventricular septum, the latter by symmetric hypertrophy of the septum and free left ventricular wall. Septal hypertrophy affects the initial phase of diastolic filling of the left ventricle as appears from longer time of isovolume relaxation and low peak rate of early transmitral blood flow; it does not influence diastolic function of the right ventricle. Hypertrophy of the free left ventricular wall disturbs the final stage of early diastolic filling of both right and left ventricles manifest as increased duration of their slowed early filling.